Results 61 to 70 of about 500 (159)
Replacement soaking for human tankyrase 2 enables studies on substrate analogues and inhibitors
Replacement soaking, also known as cross‐soaking, is a compelling method for solving complex structures in cases where traditional soaking and co‐crystallization approaches fail. This method is demonstrated with human tankyrase 2, and new crystal structures of complexes with nanomolar inhibitors and an analogue of the substrate NAD+ are reported ...
Johan Pääkkönen +3 more
wiley +1 more source
Divergence and Sufficiency for Convex Optimization
Logarithmic score and information divergence appear in information theory, statistics, statistical mechanics, and portfolio theory. We demonstrate that all these topics involve some kind of optimization that leads directly to regret functions and such ...
Peter Harremoës
doaj +1 more source
Coherent Forecasting of Realized Volatility
ABSTRACT The QLIKE loss function is the stylized favorite of the literature on volatility forecasting when it comes to out‐of‐sample evaluation and the state of the art model for realized volatility (RV) forecasting is the HAR model, which minimizes the squared error loss for in‐sample estimation of the parameters.
Marius Puke, Karsten Schweikert
wiley +1 more source
Convex Relaxations of Bregman Divergence Clustering
Appears in Proceedings of the Twenty-Ninth Conference on Uncertainty in Artificial Intelligence (UAI2013)
Hao Cheng 0002 +2 more
openaire +3 more sources
Online Coresets for Clustering with Bregman Divergences
Work in ...
Rachit Chhaya +3 more
openaire +2 more sources
Burkholder inequality by Bregman divergence
We updated a reference, corrected constants c_p and C_p, and made small editorial changes.
Bogdan, Krzysztof, Więcek, Mateusz
openaire +2 more sources
Binary Classification with a Pseudo Exponential Model and Its Application for Multi-Task Learning
In this paper, we investigate the basic properties of binary classification with a pseudo model based on the Itakura–Saito distance and reveal that the Itakura–Saito distance is a unique appropriate measure for estimation with the pseudo model in the ...
Takashi Takenouchi +2 more
doaj +1 more source
Research on clustering spatio-temporal data to extract mobility patterns requires further development, as most existing studies do not simultaneously integrate data along both spatial dimensions and temporal dimensions but instead focus on only one ...
Qian Liu +4 more
doaj +1 more source
Forest degradation reduces acoustic partitioning in tropical avian communities
The acoustic niche hypothesis posits that species partition acoustic space by frequency and time to avoid signal masking, and that any local loss of species leaves detectable gaps in co‐evolved soundscapes. However, loss, fragmentation and disturbance of habitat often lead to species turnover, and as sensitive species are lost, generalist species ...
Jennifer A. Darby +7 more
wiley +1 more source
EFFICIENCY BOUNDS FOR ALGORITHMS WITH BREGMAN DIVERGENCE
In this paper, variants of extrapolation from the past algorithm and operator extrapolation algorithm with Bregman divergence for solving variational inequalities with monotone and Lipschitz-continuous operators, which act in a finite-dimensional real linear space, are investigated. Main results: efficiency bounds for the gap function.
openaire +2 more sources

