Results 31 to 40 of about 17,423 (140)

Briarane-type diterpenoids, the inhibitors of osteoclast formation by interrupting Keap1-Nrf2 interaction and activating Nrf2 pathway.

open access: yesEuropean journal of medicinal chemistry, 2022
Chemoinformatic and bioassay-guided fractionation of a gorgonian coral Junceella juncea resulted in the isolation of 45 briarane-type diterpenoids, of which 16 new analogues were characterized.
Xinyi Qi   +6 more
semanticscholar   +1 more source

Enhancing Bioactivities and Chemical Properties of A Marine Briarane-type Diterpenoid With Late-Stage Diversification [PDF]

open access: yes, 2023
Excavatolide B (1, ExcB), a briarane-type diterpenoid isolated from Formosan gorgonian Briareum stechei, exhibits promising anti-inflammatory activity with low cytotoxicity. In this study, we report the structure-activity relationship of ExcB derivatives
Hong, Zhuang   +8 more
core   +1 more source

Survey of Briarane-Type Diterpenoids – Part IV

open access: yesHETEROCYCLES, 2011
The structures, names, biological activities, and references of 137 briarane-type diterpenoids are summarized. All briaranes mentioned in this review article were obtained from various octocorals including the specimens belonging to the genus Briareum, Ellisella, Gorgonella, Junceella, Subergorgia, Renilla, and Pachyclavularia.
Ping-Jyun Sung   +9 more
  +7 more sources

Marine Invertebrate Natural Products for Anti‐Inflammatory and Chronic Diseases

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
The marine environment represents a relatively available source of functional ingredients that can be applied to various aspects of food processing, storage, and fortification. Moreover, numerous marine invertebrates based compounds have biological activities and also interfere with the pathogenesis of diseases.
Kalimuthu Senthilkumar   +2 more
wiley   +1 more source

Chlorine-containing polyacetoxybriarane diterpenoids from the octocoral Junceella fragilis. [PDF]

open access: yesRSC Adv
[[abstract]]The chemical screening of an octocoral identifed as Junceella fragilis has led to the isolation of five chlorinated briarane-type diterpenoids, including three known metabolites, gemmacolide X (1), frajunolide I (2), and fragilide F (3 ...
Do HN   +10 more
europepmc   +2 more sources

Briarenols C–E, New Polyoxygenated Briaranes from the Octocoral Briareum excavatum

open access: yesMolecules, 2017
Three new polyoxygenated briarane diterpenoids, briarenols C–E (1–3), were isolated from the octocoral Briareum excavatum. The structures of briaranes 1–3 were elucidated by interpretation of spectroscopic data, and the methylenecyclohexane ring in 1 was
Nan-Fu Chen   +7 more
doaj   +1 more source

Torsional steering as friend and foe: development of a synthetic route to the briarane diterpenoid stereotetrad. [PDF]

open access: yesOrg Biomol Chem, 2017
Two synthetic routes to the briarane stereotetrad have been investigated. The first route employed a boron aldol reaction to establish the stereogenic all-carbon quaternary carbon (C1). In this case, it was found that torsional steering in the transition state led to the formation of the undesired configuration at this position.
Moon NG, Harned AM.
europepmc   +4 more sources

Antifouling briarane type diterpenoids from South China Sea gorgonians Dichotella gemmacea [PDF]

open access: yes, 2013
Our continued investigation on the South China Sea gorgonian Dichotella gemmacea led to the isolation of 16 new briarane-type diterpenoids, dichotellides F-U (1-16), along with 18 known analogues (17-34). Their structures were determined by MS, 1D and 2D
Han, Zhuang   +8 more
core   +3 more sources

Briareolate Esters from the Gorgonian <em>Briareum asbestinum</em>

open access: yesMarine Drugs, 2012
Two new briarane diterpenoids briareolate esters J (<strong>1</strong>) and K (<strong>2</strong>) were isolated from the methanolic extract of the octocoral <em>Briareum</em><em> asbestinum </em>collected ...
Lyndon M. West   +5 more
doaj   +1 more source

Briarane-Type Diterpenoids from the Okinawan Soft Coral Pachyclavularia violacea [PDF]

open access: yes, 2016
Four new briarane-type diterpenoids, pachyclavulides A (1), B (2), C (3), and D (4), were isolated from the Okinawan soft coral Pachyclavularia violacea.
Miwako Aoyagi (2653219)   +4 more
core   +1 more source

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