Results 21 to 30 of about 68,783 (281)

Quality, Non-clinical and Clinical Considerations for Biosimilar Monoclonal Antibody Development: EU, WHO, USA, Canada, and BRICS-TM Regulatory Guidelines [PDF]

open access: yes, 2018
Objective: The aim was to critically evaluate well-established regulatory agencies mAb biosimilar guidelines for development and marketing authorization about quality, efficacy and safety and compare to BRICS-TM regulations to identify challenges ...
Anvisa   +20 more
core   +5 more sources

Regional Dimensions of BRICS Cooperation

open access: yesМеждународная аналитика, 2022
Since the beginning, BRICS has been viewed as an element of global governance system. Recently, however, it became necessary to adapt the BRICS format to the new challenges of the world system, not only at the global, but also at the regional levels, as ...
M. L. Lagutina
doaj   +1 more source

AN OVERVIEW OF CHINESE ACTION AND PRESENCE AT AFRICA’S ENERGY TRANSITION

open access: yesRevista Tempo do Mundo, 2023
The energy transition is a necessary process to contain global warming. Some essential elements for its achievement are financing from more developed countries and collaboration between countries, especially with technology transfer.
Caroline Chagas de Assis   +1 more
doaj   +1 more source

A Formal Framework for Concrete Reputation Systems [PDF]

open access: yes, 2005
In a reputation-based trust-management system, agents maintain information about the past behaviour of other agents. This information is used to guide future trust-based decisions about interaction.
Krukow, K., Nielsen, M., Sassone, V.
core   +2 more sources

Automatic annotation of the bHLH gene family in plants

open access: yesBMC Genomics, 2023
Background The bHLH transcription factor family is named after the basic helix-loop-helix (bHLH) domain that is a characteristic element of their members. Understanding the function and characteristics of this family is important for the examination of a
Corinna Thoben, Boas Pucker
doaj   +1 more source

Trade Integration and Export Aspiration: Evidence from India’s Trade in Goods with BRICS Countries

open access: yesOrganizations and Markets in Emerging Economies, 2022
The purpose of this study was to examine the dynamics of trade between India and the BRICS countries as well as to gauge the relative strength of Indian exports to those nations.
Mudaser Ahad Bhat   +2 more
doaj   +1 more source

The US Dollar as a Prerequisite for the Crisis Potential of the Global Monetary and Financial System

open access: yesФинансы: теория и практика
The crisis of the global monetary and financial system based on the US dollar has been the focus of attention of the international academic community for a long time.
A. V. Kuznetsov
doaj   +1 more source

SCIENTIFIC COOPERATION ACROSS THE BRICS

open access: yesBRICS Law Journal, 2020
The creation of the BRICS as a non-traditional international organization in the status of a global forum brings new meaning to the norm-setting of international organizations, including in the field of scientific cooperation. This paper aims to identify
M. Astakhova
doaj   +1 more source

Globalisation: Recent traits and challenges [PDF]

open access: yes, 2019
This special issue gathers together twelve papers that revisit a range of core topics in the field of international economics. These papers were presented at the XIX Conference on International Economics (CIE) held in Vila‐Real (Spain) on 28th–29th June ...
Cuadros, Ana, Ordonez, Javier
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

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