Gastroenterologists' attitudes and challenges toward treat-to-target strategies in inflammatory bowel disease: a multinational survey. [PDF]
You Z +7 more
europepmc +1 more source
Auto‐inducible expression of chimeric antigen receptor T cells using the NR4A1 promoter
The NR4A1 promoter is a compact auto‐inducible promoter to drive CAR expression in T cells. Compared with EF1α, or existing synthetic antigen‐inducible promoters, NR4A1 is more compact and ensures that resting CAR T cells express reduced baseline CAR. NR4A1 allows rapid induction upon antigen encounter with reduced T‐cell exhaustion.
Samuel WJ Smith‐Bell +5 more
wiley +1 more source
Burden and trends of early-onset gastric cancer in the 11 BRICS countries (2025 expansion): 1990-2021 with projections to 2035. [PDF]
Li X +13 more
europepmc +1 more source
ABSTRACT Aims To develop a conceptual model integrating Robinson's Theory of Trust and Watson's Caritas Processes to guide trust‐building approaches and caring practices that support adolescents and young adults with HIV during the healthcare transition from paediatric to adult care.
Emily Anne Barr, Sara Horton‐Deutsch
wiley +1 more source
Comparative analysis of the lethality pattern of Covid-19 and the response of BRICS countries to the pandemic in the context of multilateralism: An ecological study. [PDF]
Martins TCF +4 more
europepmc +1 more source
ABSTRACT Objective To identify latent profiles of hospital nurses based on the combination of occupational demands, psychological symptoms and psychological flexibility. Examine how these profiles relate to job turnover intentions. Design Cross‐sectional online survey.
Marie Charlotte Mollet +3 more
wiley +1 more source
Liver cancer burden attributable to high body mass index and high fasting plasma glucose in BRICS countries (1990-2021): a Global Burden of Disease 2021 analysis with projections to 2050. [PDF]
Cai J, Lan Y, Wang Y, Cheng H, Xu S.
europepmc +1 more source
Systematic review (51 studies; 547 patients) indicates dupilumab may unmask/worsen CTCL (mainly MF/SS). A French Delphi consensus recommends rigorous diagnostic workup, avoiding dupilumab in confirmed CTCL, discontinuing upon diagnosis, and favouring methotrexate or phototherapy.
Florent Amatore +8 more
wiley +1 more source
Temporal trends in the incidence and mortality of kidney cancer across BRICS from 1990 to 2021: an age-period-cohort analysis. [PDF]
Wang Y, Wang Z, Shuang W.
europepmc +1 more source
Do robots boost productivity? A quantitative meta‐study
ABSTRACT This meta‐study analyzes the productivity effects of industrial robots. More than 1800 estimates from 85 primary studies are collected. The meta‐analytic evidence suggests that robotization has so far provided, at best, a small boost to productivity. There is strong evidence of publication bias in the positive direction.
Florian Schneider
wiley +1 more source

