Results 51 to 60 of about 6,246 (262)

Prognostic Impact of FLT3‐ITD Allelic Ratio in AML Patients Treated With High‐Dose Anthracycline and a FLT3 Inhibitor

American Journal of Hematology, EarlyView.
ABSTRACT The prognostic value of FLT3 internal tandem duplication (FLT3‐ITD) in acute myeloid leukemia (AML) has traditionally been stratified according to the ITD/wild‐type allelic ratio (AR) and NPM1 co‐mutation status. We evaluated the prognostic impact of FLT3‐ITD AR in 459 newly diagnosed AML patients younger than 60 years enrolled in the ...
Mathieu Leclerc, Etienne Audureau, Nicolas Duployez, Mathilde Hunault, Emmanuelle Tavernier, Cécile Pautas, Sarah Bertoli, Emmanuel Raffoux, Marie‐Anne Hospital, Tony Marchand, Maël Heiblig, Sylvain Chantepie, Martin Carre, Pierre Peterlin, Maria‐Pilar Gallego‐Hernanz, Romain Guieze, Célestine Simand, Pascal Turlure, Anne Huynh, Emilie Lemasle, Ludovic Gabellier, Juliette Lambert, Felipe Suarez, Samy Chraibi, Laurence Sanhes, Karine Celli‐Lebras, Ariane Mineur, Claude Gardin, Jean‐Valère Malfuson, Thomas Cluzeau, Norbert Vey, Régis Peffault de Latour, Lucie Rigolot, Isabelle Luquet, Dominique Penther, Raphael Itzykson, Eric Delabesse, Jean‐François Hamel, Stéphane de Botton, Arnaud Pigneux, Hervé Dombret, Claude Preudhomme, Christian Recher, Pierre‐Yves Dumas   +43 more
wiley   +1 more source

Shikonin-loaded porous graphdiyne nanofilm on titanium surface for enhanced antibacterial activity and osseointegration

Bioactive Materials
Bacterial infection, peri-implant inflammation, and poor osseointegration are primary causes of failure in titanium (Ti)-based implants. Surface functionalization provides a simple and effective strategy to overcome these challenges.
Xiaojing Zhang, Kexin Li, Yingqi Liu, Yi Han, Kun Xu, Xi Rao, Selvakumar Murugesan, Valentim A.R. Barão, En-Tang Kang, Liqun Xu   +9 more
doaj   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Genetic factors explaining anthocyanin pigmentation differences

BMC Plant Biology
Background Anthocyanins are important contributors to coloration across a wide phylogenetic range of plants. Biological functions of anthocyanins span from reproduction to protection against biotic and abiotic stressors.
Maria F. Marin-Recinos, Boas Pucker
doaj   +1 more source

On the Way to BRICS+ Digital Sovereignty: Opportunities and Challenges of a New Era

BRICS Law Journal
A new era for BRICS has begun with the desire of new countries to join BRICS. This expansion, the BRICS+, poses several challenges and opportunities for the renewed alliance, particularly concerning the digital sovereignty of the countries.
E. Gromova, D. Brantes Ferreira
doaj   +1 more source

A multi‐task deep learning–based approach to identify and assess dry root rot disease in chickpea

Applications in Plant Sciences, EarlyView.
Abstract Premise Dry root rot (DRR), an emerging global disease exacerbated by drought, affects a wide range of crops. The disease symptoms are manually scored for large‐scale germplasm screening to identify disease‐resistant varieties and test transgenic lines and other varieties.
Piyush Priya, Joe Johnson, Athimoolam Durgadevi, Navaneeth Vinayachandran, Meghna Pillai, Bharat Maitraya, Muthukumar V. Bagavathiannan, Muthappa Senthil‐Kumar   +7 more
wiley   +1 more source

The history of BRICS' International Relations (2009-2019): discourses, innovation and senstitivities

Revista Conjuntura Austral, 2020
The article discuss the main historical movements on BRICS international relations between 2009-2019: the emergence of narratives about success and failure of the BRICS; the capability of BRICS to promote innovations in the global order, and the ...
Thiago Gehre
doaj   +1 more source

Second‐Generation Polyhydroxybutyrate Production From Pretreated Corn Lignocellulosic Fraction as a Strategy to Repurpose by Products From the Corn‐Processing Chain

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Lignocellulosic residues are non‐cost, non‐edible, renewable feedstocks that can be used in polyhydroxybutyrate (PHB) production. PHB is a bioplastic synthetized by microorganisms, formed intracellularly under stressful growth conditions; however, its production costs are high, representing the major drawback for fossil‐based plastics ...
Clara Matte Borges Machado, Luciana Porto de Souza Vandenberghe, Ariane Fátima Murawski de Mello, Gustavo Amaro Bittencourt, Alexandra M. Rozhkova, Ivan N. Zorov, Susan Grace Karp, Vittoria Gomes Michelin, Carlos Ricardo Soccol   +8 more
wiley   +1 more source

The RIC Potential Amid Growing Indian-Chinese

Международная аналитика, 2018
The article aims at assessing the potential of trilateral cooperation of Russia, China and India amid growing geopolitical and economic contradictions between India and China in recent years, as well as the role of Russia in strengthening trilateral ...
E. Arapova
doaj   +1 more source

Fiscal policy in the BRICs [PDF]

Studies in Nonlinear Dynamics & Econometrics, 2013
Abstract This paper assesses the macroeconomic impact of fiscal policy shocks for four key emerging market economies – Brazil, Russia, India and China (BRICs) – using a fully simultaneous system of equations. We also estimate fiscal policy rules and analyze the importance of nonlinearity using a smooth transition (STR) model.
Fredj Jawadi, Sushanta K. Mallick, Ricardo M. Sousa   +2 more
openaire   +4 more sources