Results 111 to 120 of about 1,020,994 (316)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Traffic data collection using a bridge-weigh-in-motion system in a cable-stayed bridge

open access: yes, 2017
Reliable live traffic data collection is crucial for effective pavement life prediction, fatigue estimation, vibration control, maintenance, and condition assessment of the bridge structures.
Samali, Bijan (R17646)   +3 more
core  

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Experimental Evaluation of Highway Bridge Fingerplates Under Cyclic Loading

open access: yesBuildings
Fingerplate expansion joints are commonly used in bridges to accommodate large movements in bridge decks, often due to thermal expansion or contraction.
Mohammed Mutnbak   +4 more
doaj   +1 more source

Sereno Bridge Civil War letters

open access: yes
This collection contains ten letters written at Helena, Ark., by Sereno Bridge while he was serving with Company G of the 15th Illinois Cavalry, as well as a transcription of each ...
Bridge, Sereno, 1820-1888
core  

The proposed Australasian composite bridge standard, AS/NZS 5100 Part 6, Steel and composite construction

open access: yes, 2013
This paper details the ongoing progress by the Australian Standards Committee BD-90-06 on the Australasian Standard for Bridge Design, Steel and Composite Construction, AS/NZS 5 100 Part 6 which is currently being prepared for public comment and is ...
Uy, Brian   +2 more
core  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Evaluation of the Buena Vista IBRD Bridge: A Furthering of Accelerated Bridge Construction in Iowa;TR-605, February 2012

open access: yes, 2012
The need to construct bridges that last longer, are less expensive, and take less time to build has increased. The importance of accelerated bridge construction (ABC) technologies has been realized by the Federal Highway Administration (FHWA) and the ...

core  

Vehicle-bridge dynamic interaction using finite element modelling

open access: yes, 2010
First investigations on the dynamic response of bridges due to moving loads were motivated by the collapse of the Chester railway bridge in the UK in the middle of the 19th century.
Arturo Gonzalez, González, Arturo
core   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

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