Results 101 to 110 of about 2,106,514 (153)

Venetoclax and azacitidine for younger acute myeloid leukemia patients independent of fitness for intensive chemotherapy. [PDF]

Haematologica
Watts J, Madarang E, Abbott D, Hart P, Sohalski C, Zoso A, Dell-Martin J, Belachew A, Amaya ML, Kent A, McMahon C, Schwartz M, Sekeres MA, Smith C, Bradley T, Taylor J, Chandhok N, Venugopal S, Jordan C, Berg M, Haag M, Willard N, Aisner D, Schowinsky J, Pan Z, Zhang J, Gutman JA, Pollyea DA.   +27 more
europepmc   +1 more source

Halide Bond Assisted Double Desymmetrization of Meso-Dicarboxylic Acids with Symmetrical Olefins via Asymmetric Halogenation. [PDF]

Angew Chem Int Ed Engl
Zhang Q, Wang H, Tse YS, Yeung YY.
europepmc   +1 more source

Venetoclax-based therapy in high-risk patients with relapsed/refractory multiple myeloma harboring t(11;14): a case report and review of the literature. [PDF]

J Med Case Rep
Yin J, Zhou X, Zhong Y.
europepmc   +1 more source

Covalent Targeting and Thermostabilization of Oncogenic R280K and R273H Mutants p53 by Small Molecule RVJB59. [PDF]

ChemMedChem
Ferreira RJF, Gonçalves LM, Mori M, Antunes AMM, Leandro AP, Santos MMM.   +5 more
europepmc   +1 more source

Linerixibat: First Approval. [PDF]

Drugs
Hoy SM.
europepmc   +1 more source

Dimerisation of aryl-substituted bicyclobutanes (BCBs): revealing a new mode of 1,3-dipolar background reactivity. [PDF]

Chem Sci
George M, Knyazev DA, Swiatek K, von Köller HF, Werz DB.   +4 more
europepmc   +1 more source

Organocatalytic Asymmetric Synthesis of Spiro-Bridged and Spiro-Fused Heterocyclic Compounds Containing Chromane, Indole, and Oxindole Moieties.

Organic Letters, 2018
Following the reactivity inversion strategy, two different two-step sequences were designed and successfully applied to the asymmetric synthesis of spiro-bridged and spiro-fused heterocyclic compounds, which combined chromane, indole, and oxindole, three
Zhi-Hao You, Yinghan Chen, Yu Tang, Yan-Kai Liu   +3 more
semanticscholar   +2 more sources

Nazarov Cyclization/Internal Redox Cyclization Sequence for the Synthesis of N-Heterocyclic Bridged Ring Systems.

Organic Letters, 2016
A 1,6 conjugate addition/Nazarov electrocyclization/internal redox cyclization sequence was developed. Various 5-hydroxycyclopentenones were made through the 1,6-conjugate addition initiated Nazarov reaction with excellent diastereoselectivities.
Yu-Wen Huang, A. Frontier
semanticscholar   +3 more sources

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Unsaturated Heterocyclic Systems. LXXXIX. Reactivity of Bicyclo [4.2.2] Deca-2,4,7,9-Tetraene Derivatives Under Conditions of Uniparticulate Electrophilic Addition. Intramolecular Capture of Zwitterionic Bridged 1,4-Bishomotropylium (Bicyclo [4.3.1] Deca-2,4,7-Trienyl) Intermediates

Journal of Organic Chemistry, 1973
L. Paquette, M. Broadhurst
exaly   +2 more sources

Domino Reactions for the Synthesis of Bridged Bicyclic Frameworks: Fast Access to Bicyclo[n.3.1]Alkanes

Chemical Society Reviews, 2011
In the current bid for synthetic efficiency{,} multiple bond-forming transformations are becoming a key concept in organic synthesis. In this context{,} domino protocols have become increasingly common in the synthesis of bicyclic systems.
Giorgio Giorgi, José Carlos Menendez, Pilar Lopez-Alvarado   +2 more
exaly   +2 more sources