Results 41 to 50 of about 1,748,469 (290)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Adaptive Image-Defogging Algorithm Based on Bright-Field Region Detection

Photonics
Image defogging is an essential technology used in traffic safety monitoring, military surveillance, satellite and remote sensing image processing, medical image diagnostics, and other applications.
Yue Wang, Fengying Yue, Jiaxin Duan, Haifeng Zhang, Xiaodong Song, Jiawei Dong, Jiaxin Zeng, Sidong Cui   +7 more
doaj   +1 more source

BRIGHT HOT IMPACTS BY ERUPTED FRAGMENTS FALLING BACK ON THE SUN: MAGNETIC CHANNELLING [PDF]

The Astrophysical Journal, 2016
ABSTRACT Dense plasma fragments were observed to fall back on the solar surface by the Solar Dynamics Observatory after an eruption on 2011 June 7, producing strong extreme-ultraviolet brightenings. Previous studies investigated impacts in regions of weak magnetic field. Here we model the
Petralia, A., REALE, Fabio, Orlando, S., Testa, P.   +3 more
openaire   +3 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Operation of normal-conducting rf cavities in multi-Tesla magnetic fields for muon ionization cooling: A feasibility demonstration

Physical Review Accelerators and Beams, 2020
Ionization cooling is the preferred method for producing bright muon beams. This cooling technique requires the operation of normal conducting, radio-frequency (rf) accelerating cavities within the multi-tesla fields of dc solenoid magnets.
D. Bowring, A. Bross, P. Lane, M. Leonova, A. Moretti, D. Neuffer, R. Pasquinelli, D. Peterson, M. Popovic, D. Stratakis, K. Yonehara, A. Kochemirovskiy, Y. Torun, C. Adolphsen, L. Ge, A. Haase, Z. Li, D. Martin, M. Chung, D. Li, T. Luo, B. Freemire, A. Liu, M. Palmer   +23 more
doaj   +1 more source

ON THE ACTIVE REGION BRIGHT GRAINS OBSERVED IN THE TRANSITION REGION IMAGING CHANNELS OF IRIS [PDF]

The Astrophysical Journal, 2016
ABSTRACT The Interface Region Imaging Spectrograph (IRIS) provides spectroscopy and narrow band slit-jaw (SJI) imaging of the solar chromosphere and transition region at unprecedented spatial and temporal resolutions. Combined with high-resolution context spectral imaging of the photosphere and chromosphere as provided by the Swedish 1 m
H. Skogsrud, L. Rouppe van der Voort, B. De Pontieu   +2 more
openaire   +3 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Letter to Richard Bright from Wm Bright

, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/240104Re:
Bright Family
core   +2 more sources

The Sequin Illusion

i-Perception, 2019
The Sequin Illusion can be seen when shapes are drawn in dotted lines, against a background of different brightness. This can be done either with bright dots over a dark background or with dark dots over a bright background, though the latter usually ...
Yi-Tsen Kuo, Philip Tseng
doaj   +1 more source

Inspection and Defect Detection Using Digital Holography for Advanced Packaging [PDF]

EPJ Web of Conferences
Advanced packaging processes such as hybrid bonding require defect-free surfaces with nanometre-level cleanliness. Conventional bright-field and dark-field inspection struggle on patterned substrates: bright-field contrast is dominated by the nominal ...
Mukundakumar Balasubrahmaniyam, Barczyk René, Matsuura Shimpei   +2 more
doaj   +1 more source