Results 111 to 120 of about 1,354 (149)

Vitreous concentration of topically applied brimonidine tartrate 0.2%

Ophthalmology, 2001
To determine the vitreous concentration of brimonidine after topical administration of Alphagan.Prospective observational case series.Eighteen patients scheduled for elective pars plana vitrectomy.Brimonidine tartrate, 0.2%, was topically administered twice or three times daily for 4 to 14 days preoperatively in 13 patients.
Kent, A. R., Nussdorf, J. D., David, R., Tyson, F., Small, D., Fellows, D.   +5 more
openaire   +4 more sources

Brimonidine tartrate for the treatment of facial flushing and erythema in rosacea

Expert Review of Clinical Pharmacology, 2014
Rosacea is a chronic inflammatory dermatologic condition that can often be disfiguring with significant negative impact on patients' quality of life. Sanrosa (brimonidine tartate) is a novel therapeutic agent targeting the facial flushing and erythema of rosacea through its α₂ adrenergic receptor agonist activity. The goal of this article is to discuss
Lana X, Tong, Angela Yen, Moore
openaire   +2 more sources

Comparison of the neuroprotective effects of brimonidine tartrate and melatonin on retinal ganglion cells

International Ophthalmology, 2017
We aimed to compare the neuroprotective effects of brimonidine tartrate (BRT) and melatonin (MEL) on retinal ganglion cells (RGCs) in a rat glaucoma model.Thirty-six adult Wistar albino rats were allocated into six groups: control (C), glaucoma (G), BRT, MEL, G + BRT and G + MEL.
Guzel Elif, Ilgaz Yalvac, Signem Eyuboglu   +2 more
exaly   +3 more sources

Effect of brimonidine tartrate 0.2% ophthalmic solution on pupil size

Journal of Cataract and Refractive Surgery, 2004
To evaluate the effect of brimonidine tartrate 0.2% ophthalmic solution on pupil size under scotopic and photopic luminance conditions in persons considering laser refractive surgery.Ophthalmic Health Center, Tel Aviv, Israel.The pupil size was measured in 36 eyes of 36 participants under scotopic and photopic conditions using the Colvard pupillometer (
Anat, Kesler, Gabi, Shemesh, Levi, Rothkoff, Moshe, Lazar   +3 more
openaire   +2 more sources

Effect of brimonidine tartrate 0.10% ophthalmic solution on pupil diameter

Journal of Cataract and Refractive Surgery, 2011
To evaluate the effect of brimonidine tartrate 0.10% ophthalmic solution on pupil diameter under light and dark luminance conditions.Ophthalmology Department, Tel Aviv Medical Center, Tel Aviv, Israel.Case series.The pupil diameter was measured with a Colvard pupillometer in eyes of healthy volunteers under light (5.0 candelas [cd]/m(2)) and dark (0.0 ...
Gabi, Shemesh, Elad, Moisseiev, Moshe, Lazar, Anat, Kesler   +3 more
openaire   +2 more sources

Effect of Brimonidine Tartrate 0.15% on Scotopic Pupil: Controlled Trial

Journal of Ocular Pharmacology and Therapeutics, 2007
The aim of this study was to evaluate the duration of the effect of one single dose of brimonidine tartrate 0.15% on pupil diameter, under scotopic conditions, when applied topically in 1 eye of normal subjects.The eyes of 19 normal volunteers were randomized so that 1 eye had 1 drop of brimonidine tartrate 0.15% and the other received no medication ...
Gerente, Vanessa M., Biondi, Adriano C., Barbosa, Carolina P., Lottenberg, Claudio L., Paranhos, Augusto   +4 more
openaire   +3 more sources

Chitosan nanoparticles for controlled delivery of brimonidine tartrate to the ocular membrane

Die Pharmazie, 2011
Various efforts have been made to improve the bioavailability and to prolong the residence time of eye drops. Drug loaded polymeric nanoparticles offer several favorable biological properties. Thus, brimonidine tartrate (BT) loaded chitosan (CS) nanoparticles were prepared by inducing the ionic gelation upon addition of sodium tripolyphosphate (TPP ...
Shinde, U. A., Singh, K. H.
openaire   +2 more sources

Vitreous and Aqueous Concentrations of Brimonidine Following Topical Application of Brimonidine Tartrate 0.1% Ophthalmic Solution in Humans

Journal of Ocular Pharmacology and Therapeutics, 2015
To determine the vitreous and aqueous concentrations of brimonidine after topical application of the ophthalmic solution 0.1%.The prospective observational case series included patients with an idiopathic epiretinal membrane or macular hole who were scheduled for a pars plana vitrectomy.
Yoshihiro, Takamura, Takeshi, Tomomatsu, Takehiro, Matsumura, Yuji, Takihara, Seiko, Kozai, Shogo, Arimura, Satoshi, Yokota, Masaru, Inatani   +7 more
openaire   +2 more sources

Miotic effect of brimonidine tartrate 0.15% ophthalmic solution in normal eyes

Journal of Cataract and Refractive Surgery, 2004
To evaluate the effect of brimonidine tartrate 0.15% ophthalmic solution (Alphagan P) on pupil diameter in eyes of healthy adults under different luminance conditions.Center for Refractive Surgery, Ophthalmology Service, Department of Surgery, Walter Reed Army Medical Center, Washington, DC, USA.Using a Colvard pupillometer, the pupil diameter was ...
John E, Thordsen, Kraig S, Bower, Brent B, Warren, Richard, Stutzman   +3 more
openaire   +2 more sources

Effect of single and multiple doses of 0.2% brimonidine tartrate in the glaucomatous Beagle

Veterinary Ophthalmology, 2002
AbstractThe objective of this study was to evaluate the changes in intraocular pressure (IOP) in glaucomatous dogs after instillations of 0.2% brimonidine once, twice and three times daily in single day studies, and after twice and three times daily for 4 days in multiple dose studies. We studied eight Beagles with inherited primary open angle glaucoma.
Kirk N, Gelatt, Edward O, MacKay
openaire   +2 more sources