Results 51 to 60 of about 24,449 (196)

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare   +7 more
wiley   +1 more source

Enhancing Osteogenesis through Bio‐Inspired Recombinant Coral Protein Galaxin by Targeting Mitochondrial Metabolism and ATP Production

open access: yesAdvanced Science, EarlyView.
The study highlights the potential of recombinant galaxin (a coral protein) as a novel and effective biomaterial for bone regeneration. It binds to ATP synthase subunit β (ATP5B) in mouse pre‐osteoblasts, thereby causing increased ATP production and mitochondrial activity.
Fei Yu   +6 more
wiley   +1 more source

Mg‐doped α‐Ga2O3 Nanorods for the Construction of Photoelectrochemical‐Type Self‐Powered Solar Blind UV Photodetectors and Underwater Imaging Application

open access: yesAdvanced Science, EarlyView.
A low‐cost hydrothermal technique is employed to optimize the synthesis of Mg‐doped α‐Ga2O3 nanorod arrays. Compared to undoped α‐Ga2O3 photodetectors, the photocurrent response is increased by 435%, with a peak responsivity of 34.54 mA W−1. Furthermore, a 5 × 5 PEC‐SBPD array based on Mg‐doped α‐Ga2O3 nanorod arrays is constructed for underwater ...
Xin Zhou   +9 more
wiley   +1 more source

Anion Exchange Membrane Seawater Electrolysis at 1.0 A cm−2 With an Anode Catalyst Stable for 9000 H

open access: yesAdvanced Science, EarlyView.
The CAPist‐S1 catalyst containing dense interlayer structure is synthesized by one‐step autologous method. The dense NiFe LDH interlayer inhibits the Cl− ions penetration onto metal substrate, significantly improving the corrosion resistance. The obtained catalyst requires an overpotential of 220 mV at 1.0 A cm−2 and exhibits excellent durability over ...
Jian Du   +6 more
wiley   +1 more source

A Bias‐Tunable Multispectral Photodetector Based on a GaN/TexSe1‐x Homo‐Type Heterojunction with a Unidirectional Barrier

open access: yesAdvanced Science, EarlyView.
A bias‐tunable multispectral photodetector based on a TexSe1‐x/GaN homo‐type heterojunction with a unidirectional barrier is proposed. By modulating the bias polarity and magnitude, the device's spectral response range can be extended from UV to the SWIR region.
Weijie Liu   +14 more
wiley   +1 more source

OcuPair, a Novel Photo‐crosslinkable PAMAM Dendrimer‐Hyaluronic Acid Hydrogel Bandage/Bioadhesive for Corneal Injuries and Temporary Corneal Repair

open access: yesAdvanced Science, EarlyView.
A schematic diagram showing the OcuPair adhesive hydrogel formulation loaded into the final delivery device and applied over the full‐thickness corneal wound in an in vivo rabbit model of corneal injury followed by in situ crosslinking to form a transparent hydrogel bandage sealing the wound.
Siva P. Kambhampati   +6 more
wiley   +1 more source

Nanoconfinement Engineering of Covalent Organic Frameworks in Polyamide Membranes for High‐Perselectivity Li+/Mg2+ Separation

open access: yesAdvanced Science, EarlyView.
A nanoconfinement strategy using porous COF layers is developed to regulate interfacial polymerization and prepare thin, uniform PA membranes. The COF layer provides confined spaces and abundant interaction sites, effectively controlling monomer distribution and reaction kinetics.
Shuzhen Zhao   +9 more
wiley   +1 more source

Porous Aromatic Framework with Multifunctional Sites for Effective Recovery of Various Trace Iodine Species From Water

open access: yesAdvanced Science, EarlyView.
A PAF adsorbent with multifunctional sites framework is developed for the recovery of environment iodine. Benefiting from the high density and accessibility of the favorable Coulomb interaction sites for iodide (I3− and I−) as well as the charge transfer sites for iodine molecules (I2), the PAF adsorbent realizes recording adsorption capacity for ...
Yue Ma   +8 more
wiley   +1 more source

Ultra–Efficient and Selective Gold Separation via Second–Sphere Coordination of Aurous Dihalide Using a Nonporous Amorphous Superadsorbent

open access: yesAdvanced Science, EarlyView.
A covalent organic superphane cage serves as a nonporous amorphous superadsorbent for highly efficient and selective gold separation. This material uniquely captures linear aurous dihalide ions, achieving exceptional uptake capacity and selectivity, and proving effective even in seawater, offering a scalable, eco–friendly solution to gold scarcity ...
Wei Zhou   +6 more
wiley   +1 more source

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