Results 41 to 50 of about 1,483,623 (310)

Pulling together or pulling apart? Solidarity in the post-crisis United Kingdom [PDF]

open access: yes, 2018
Solidarity in contemporary Britain has come under pressure not only as a result of the global financial crisis and the ensuing austerity measures but also against a backdrop of constitutional volatility from the Scottish independence referendum in 2014 ...
A Dunn   +46 more
core   +3 more sources

Introduction: Layered Landscapes [PDF]

open access: yes, 2020
This Special Issue of Arts investigates a series of creative projects focused upon and sited within certain peripheral landscapes of northern Britain ..
Ashmore, Rupert, Holt, Ysanne
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Labour parties ideas transfer and ideological positioning : Australia and Britain compared [PDF]

open access: yes, 2016
As part of this special issue examining policy transfer between the Labour Parties in Australia and Britain, this paper seeks to explore the relationship between the two on ideological positioning.
Beech, Matt, Edwards, Belinda M.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Communicating Newman to a secular audience: the communications strategy for the canonisation of John Henry Newman

open access: yesChurch, Communication and Culture, 2020
The canonisation of John Henry Newman by Pope Francis in 2019 was an opportunity to communicate to a largely secular audience in Britain and the rest of the world the search for truth that inspired Newman’s life.
Jack Valero
doaj   +1 more source

Spenser and the Historical Revolution: Briton Moniments and the Problem of Roman Britain [PDF]

open access: yes, 1996
Curran argues that, since Roman Britain is a key to understanding the historiographical debates of Edmund Spenser\u27s time, the Roman Britain section of Briton Moniments in The Faerie Queene needs to be examined.
Curran, John E., Jr.
core   +1 more source

‘The impression is growing … that the United States is hard when dealing with us’: Ernest Bevin and Anglo-American relations at the dawn of the cold war [PDF]

open access: yes, 2012
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2012 Board of Transatlantic Studies.This article examines British Foreign Secretary Ernest Bevin's views on Anglo-American relations ...
Folly, MH
core   +1 more source

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