Results 101 to 110 of about 162,085 (250)

Pediatric sepsis in the developing world: challenges in defining sepsis and issues in post-discharge mortality

open access: yesClinical Epidemiology, 2012
Matthew O Wiens,1 Elias Kumbakumba,2 Niranjan Kissoon,3 J Mark Ansermino,4 Andrew Ndamira,2 Charles P Larson51School of Population and Public Health, University of British Columbia, Vancouver, Canada; 2Department of Pediatrics, Mbarara University of ...
Larson CP   +5 more
doaj  

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo   +8 more
wiley   +1 more source

Questioning locality: the UBC Museum of Anthropology and its hinterlands Questionando a localidade: o UBC Museum of Anthropology e os seus arredores

open access: yesEtnográfica: Revista do Centro em Rede de Investigação em Antropologia, 2007
This paper argues that locality is itself a culturally constructed category which, if not critically assessed may hide the political relations existing between museums and other institutions within a specified museumscape.
Anthony Shelton
doaj  

Increasing phospholipid biomimicry governs water permeability in droplet interface bilayers

open access: yesDroplet, EarlyView.
Increasing phospholipid biomimicry in droplet interface bilayers alters how membranes respond to “membrane‐active molecules” such as cholesterol and niacin. This shows that membranes made using synthetic lipids can overestimate small‐molecule effects, highlighting the importance of using biomimetic lipid compositions to improve physiological relevance ...
Alejandro Forigua, Katherine S. Elvira
wiley   +1 more source

Neural Network‐Based Detection of Adulterants in Opioid Samples Using IR Absorption Spectroscopy

open access: yesDrug Testing and Analysis, EarlyView.
We construct a neural network for the classification of bromazolam and fluorofentanyl in illicit opioid samples. The model outperforms a random forest classifier and shows elevated performance for low concentration samples. ABSTRACT Community‐based drug checking services are challenged in their ability to reliably detect low concentration adulterants ...
Joshua Jai   +4 more
wiley   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu   +4 more
wiley   +1 more source

The role of Rho GTPases in facial morphogenesis

open access: yesDevelopmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Development of Disordered Weight Control Behaviors and Its Progression to Eating Disorders in Canada: A Nationally Representative Microsimulation

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (ED) present a significant health burden to children, adolescents, and young adults globally. Despite the importance of disordered weight control behaviors (DWCB) in ED development, little is known about the progression from DWCB to ED.
Ye Shen   +5 more
wiley   +1 more source

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