Results 51 to 60 of about 962,234 (295)

Toward Multi(radio)metalated DNA: Enzymatic Polymerization of Metal‐Chelate‐Modified Deoxyribonucleoside Triphosphates

open access: yesAngewandte Chemie, EarlyView.
This work presents the first enzymatic polymerization of defined metal‐chelator‐modified nucleotides that leverage polymerase fidelity for uniform (radio)metal loading with successful incorporation of five different metals: Ga, In, Tb, Lu, and Y.
Antonio A. W. L. Wong   +2 more
wiley   +2 more sources

British Columbia Colonial History Conference [PDF]

open access: yes, 2020
Historians and other scholars of early British Columbia marked the 150th anniversary of the colonial foundations of the west coast province with a conference at Fulford Harbour, Salt Spring Island, on the weekend of 9-10 January ...
Mackie, Richard
core   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

open access: yesAdvanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua   +6 more
wiley   +1 more source

A Cross-Sectional Analysis of Acute Hepatitis B Virus Reported to the Vancouver Coastal Health Authority from 2000 to 2003

open access: yesCanadian Journal of Gastroenterology, 2006
BACKGROUND: Acute hepatitis B virus (HBV) transmission remains a significant public health problem despite effective vaccination and prophylaxis strategies.
Yvette Leung   +4 more
doaj   +1 more source

Transforming First Nations Health Care in British Columbia: An Organizational Challenge

open access: yesInternational Indigenous Policy Journal, 2018
Following a series of agreements on First Nations health care in British Columbia beginning in 2005, several organizations were created to contribute to the development of a system of health care for First Nations in the province, with the aim of ...
Stephen Wilmot
doaj   +1 more source

Quaternary rupture of a crustal fault beneath Victoria, British Columbia, Canada [PDF]

open access: yes, 2017
The seismic potential of crustal faults within the forearc of the northern Cascadia subduction zone in British Columbia has remained elusive, despite the recognition of recent seismic activity on nearby fault systems within the Juan de Fuca Strait.
Amos, Colin   +4 more
core   +1 more source

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

open access: yesAdvanced Science, EarlyView.
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu   +18 more
wiley   +1 more source

Taxonomic synopsis of invasive and native Spartina (Poaceae, Chloridoideae) in the Pacific Northwest (British Columbia, Washington and Oregon), including the first report of Spartina ×townsendii for British Columbia, Canada

open access: yesPhytoKeys, 2012
Five species of the grass genus Spartina are invading salt marshes along the Pacific coast of North America, of which three have been documented in British Columbia, Canada, in only the last decade. A taxonomic synopsis of the two native (S. gracilis, S.
Jeffery Saarela
doaj   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo   +13 more
wiley   +1 more source

The Community Youth Outreach Programme In Delta, British Columbia, Canada: "The Personal Touch That Works"

open access: yesRefuge, 2000
With Canada's strong multicultural policy, immigrants are encouraged to maintain their cultural values and expectations while adjusting to a new country.
Sherman Chan, Hardeep Thind, Lesley Lim
doaj   +1 more source

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