Results 51 to 60 of about 2,519,212 (279)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

open access: yesAdvanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang   +12 more
wiley   +1 more source

Additively Manufactured Porous Ceramics as Tunable Dielectrics for Passive Temperature Sensing

open access: yesAdvanced Materials Technologies, EarlyView.
Porous ceramic lattices, 3D‐printed from a multicomponent oxide ink, are integrated with LC resonators for passive wireless temperature sensing. By tuning porosity, the dielectric properties and RF response are engineered to produce distinct resonant frequency shifts with temperature. The results establish a structure‐driven approach to customizing the
Sogol Heidarishahrivar   +5 more
wiley   +1 more source

Programmable Variable‐Stiffness Multilayer Elastomer Composites With High‐Aspect‐Ratio Low‐Melting‐Point Alloy Inclusions

open access: yesAdvanced Materials Technologies, EarlyView.
High‐aspect‐ratio low‐melting‐point alloy inclusions are embedded within multilayer silicone laminates to create thermally programmable stiffness. Sequential activation of alloy‐rich layers produces four distinct mechanical states and reconfigures tendon‐driven actuator trajectories under the same load.
Palpolage Don Shehan Hiroshan Gunawardane   +4 more
wiley   +1 more source

A Cross-Sectional Analysis of Acute Hepatitis B Virus Reported to the Vancouver Coastal Health Authority from 2000 to 2003

open access: yesCanadian Journal of Gastroenterology, 2006
BACKGROUND: Acute hepatitis B virus (HBV) transmission remains a significant public health problem despite effective vaccination and prophylaxis strategies.
Yvette Leung   +4 more
doaj   +1 more source

Transforming First Nations Health Care in British Columbia: An Organizational Challenge

open access: yesInternational Indigenous Policy Journal, 2018
Following a series of agreements on First Nations health care in British Columbia beginning in 2005, several organizations were created to contribute to the development of a system of health care for First Nations in the province, with the aim of ...
Stephen Wilmot
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

open access: yesAdvanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait   +7 more
wiley   +1 more source

Biosynthesis of Spatially Differentiated Cellulose for Flexible All‐in‐one Supercapacitors

open access: yesAdvanced Science, EarlyView.
Spatially differentiated bacterial cellulose is grown by oxygen‐guided biosynthesis to form dense surface regions connected by an open fibrillar interlayer. This architecture supports electroactive material loading, ion transport, and mechanical stability in an all‐in‐one supercapacitor, showing how biological assembly can create device‐ready ...
Xin Shu   +7 more
wiley   +1 more source

Taxonomic synopsis of invasive and native Spartina (Poaceae, Chloridoideae) in the Pacific Northwest (British Columbia, Washington and Oregon), including the first report of Spartina ×townsendii for British Columbia, Canada

open access: yesPhytoKeys, 2012
Five species of the grass genus Spartina are invading salt marshes along the Pacific coast of North America, of which three have been documented in British Columbia, Canada, in only the last decade. A taxonomic synopsis of the two native (S. gracilis, S.
Jeffery Saarela
doaj   +1 more source

Lode-Gold Deposits, North-eastern British Columbia and Cariboo and Hobson Creek Areas: [PDF]

open access: yes, 1947
by Stuart S. Holland.Bulletin (British Columbia. Department of Mines) ; no. 20, pt.

core  

Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
The schematic diagram depicts a compartmentalized anti‐ferroptotic defense mechanism mediated by GSTA4. GSTA4 is upregulated and localizes to the cytoplasm in ENZR cells, where it detoxifies 4‐HNE via a non‐canonical GSH‐dependent pathway. Under oxidative stress, GSTA4 translocates to mitochondria, interacts with PGAM5, and blocks Drp1 Ser637 ...
Yong Luo   +17 more
wiley   +1 more source

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