Aims This work aimed to correlate potential links between the suspected adverse drug reaction (ADR) profile of licensed nonsteroidal androgen receptor antagonists (NSARA) with their unique chemical properties and known off‐target polypharmacology. Methods Physicochemical and polypharmacology data were curated from the Electronic Medicines Compendium ...
Simrit Dhillon +2 more
wiley +1 more source
British Columbia Children's Hospital Compass Program: Extending mental health supports for rural Northern communities. [PDF]
Tsang VWL +8 more
europepmc +1 more source
Precision medicine in paediatrics: Progress and priorities
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
Performing populist leadership online: Discursive and multimodal construction of a shared social identity. [PDF]
Jaakkola J +3 more
europepmc +1 more source
Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim +37 more
wiley +1 more source
The Despair of Identity Diffusion: Associations With Psychache and Hopelessness and the Indirect Effect of Childhood Emotional Abuse. [PDF]
Russolillo A, Hawkins C, Kealy D.
europepmc +1 more source
A scoping review of quality prescribing indicators, rules and criteria for primary care
Medication‐related problems (MRPs) place a substantial burden on the healthcare system, contributing to hospital admissions and significant healthcare costs. Quality prescribing indicators (QPIs), rules and criteria serve to educate prescribers about high risk MRPs and to monitor prescribing behaviours. This study aims to summarize existing indicators,
James Nind +6 more
wiley +1 more source
Optimization of a group-based intervention for people living with severe obesity (PROGROUP): Understanding fidelity to delivery and the patient experience. [PDF]
Hawkins L +7 more
europepmc +1 more source
The Siren's call: How social media influencers are using identity leadership to shape diagnostic label identification and self-care intentions. [PDF]
Cheng Y +4 more
europepmc +1 more source

