Results 141 to 150 of about 257,938 (322)

FireProtDB 2.0: large-scale manually curated database of the protein stability data. [PDF]

Nucleic Acids Res
Musil M, Borko S, Planas-Iglesias J, Lacko D, Rosinska M, Kabourek P, Martins LO, Tataruch M, Damborsky J, Mazurenko S, Bednar D.   +10 more
europepmc   +1 more source

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

The FEBS Journal, EarlyView.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher, Pavel Dobeš, Jan Komárek, Lukáš Faltinek, Marek Korsák, Petra Sýkorová, Josef Houser, Michaela Wimmerová   +7 more
wiley   +1 more source

Circulating MicroRNAs do not provide a diagnostic benefit over tissue biopsy in patients with brain metastases. [PDF]

Sci Rep
Ruckova M, Al Tukmachi D, Vecera M, Deissova T, Jugas R, Hermanova M, Hendrych M, Kren L, Fadrus P, Vybihal V, Valekova H, Jancalek R, Kazda T, Slaby O, Smrcka M, Sana J.   +15 more
europepmc   +1 more source

Winter‐active spiders (Clubiona) have a hyperactive antifreeze protein with a unique beta‐solenoid fold

The FEBS Journal, EarlyView.
Antifreeze proteins from winter‐active spiders were purified using their affinity for ice. After LC–MSMS characterization, corresponding transcripts were identified. The antifreeze protein folds as a β‐solenoid with a large flat ice‐binding site on one surface and can bind to ice crystals and prevent their growth at −4 °C.
Laurie A. Graham, Stano Pekár, Ina M. Hainer, Peter L. Davies   +3 more
wiley   +1 more source

Pavel Boček (31. července 1955 Nové Město na Moravě - 4. dubna 2025 Brno)

Kateřina Pražáková
openalex   +2 more sources

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

The FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal, Tomas Brom, Ivona Nečasová, Tomáš Janovič, Pavel Veverka, Naina Verma, Lukáš Uhrík, Lenka Hernychova, Ctirad Hofr   +8 more
wiley   +1 more source

Assessment of long-read strategies for the enrichment of clinically relevant breakpoints in lymphomas: towards a diagnostic implementation. [PDF]

Ann Hematol
Pardy F, Reblova K, Svozilova H, Tichy B, Pospisilova S, Kotaskova J, Navrkalova V.   +6 more
europepmc   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

MRI Predictors for Improvement Without Any Intervention of Clinical Symptoms in Patients With Lumbar Disc Herniation, Questioning the True Need for Surgery. [PDF]

Radiol Res Pract
Šprláková-Puková A, Straka M, Habas T, Čellár A, Dostál M, Barusová T, Sova M, Kryštofová S, Smrčka M.   +8 more
europepmc   +1 more source

Comptes rendus: P. Dytrt : « Le (post-)moderne dans les romans de J. Echenoz. De l’anamnèse du moderne vers une écriture du postmoderne ». Brno, 2007

, 2009
Timo Obergöker
openalex   +1 more source