Results 31 to 40 of about 56,612 (291)
Advanced Healthcare Materials, EarlyView.Fiber orientation in electrospun scaffolds affects permeability and fluid dynamics in microfluidic devices. Combining experimental data with computational fluid dynamic simulations, we show that aligned fibers enhance flow uniformity, reduce pressure and shear stress variability.
Elisa Capuana +4 more
wiley +1 more source
Guidelines for writing definitions in ontologies [PDF]
, 2017 Ontologies are being used increasingly to promote the reusability of scientific information by allowing heterogeneous data to be integrated under a common, normalized representation. Definitions play a central role in the use of ontologies both by humans
Ruttenberg, Alan +2 more
core +1 more source
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
Advanced Healthcare Materials, EarlyView.This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi +10 more
wiley +1 more source
Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior
Advanced Healthcare Materials, EarlyView.Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley +1 more source
Clinical and magnetic resonance imaging characteristics of thoracolumbar intervertenral disk extrusions and protrusions in large breed dogs [PDF]
, 2016 It has recently been shown that the fat-derived hormone adiponectin has the ability to decrease hyperglycemia and to reverse insulin resistance. However, bacterially produced full-length adiponectin is functionally inactive. Here, we show that endogenous
Beltran, E +5 more
core +4 more sources
Unravelling the identity of Pandora species (Bivalvia: Pandoridae) from Southern South America [PDF]
, 2016 Four species of Pandora have been reported from southern South America: P. cistula Gould, 1850, P. braziliensis G. B. Sowerby II, 1874, P. diffissa Mabille & Rochebrune, 1889 and P. patagonica (Dall, 1915).
Güller, Marina, Zelaya, Diego Gabriel
core +1 more source
Advanced Healthcare Materials, EarlyView.This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale +6 more
wiley +1 more source
Characteristics of Alveolar Bone Marrow Cells from Patients Undergoing Dental Extractions or Dental Implant Therapy [PDF]
, 2020 Alveolar bone marrow stromal cells (aBMSCs) play important roles in craniofacial wound healing. To establish an easy, efficient and reliable method to harvest aBMSCs, we compared three different methods: extraction socket aspiration, osteotomy aspiration
Lee, Meng H
core +2 more sources
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
Advanced Healthcare Materials, EarlyView.This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source