Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
The Charge-Transfer Motif in Crystal Engineering. Self-Assembly of Acentric (Diamondoid) Networks from Halide Salts and Carbon Tetrabromide as Electron-Donor/Acceptor Synthons [PDF]
Unusual strength and directionality for the charge-transfer motif (established in solution) are shown to carry over into the solid state by the facile synthesis of a series of robust crystals of the [1:1] donor/acceptor complexes of carbon tetrabromide ...
Hecht, Jürgen +2 more
core +1 more source
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
INTERACTION BETWEEN PANCURONIUM BROMIDE AND VECURONIUM BROMIDE
The interaction between two non-depolarizing neuromuscular blocking agents, pancuronium bromide and vecuronium bromide, has been studied at standardized levels of neuromuscular blockade and alternating the sequence of their administration, in 40 surgical patients.
O. M. Rashkovsky +2 more
openaire +4 more sources
Nitrosation of quaternary ammonium compounds in vivo in the Wistar rat [PDF]
1. Animals dosed orally with nitrite (1.5 × 10−3 mol/kg) and nonyl dimethylbenzylammonium bromide (2.9 × 10−4 mol/kg) exhibit liver damage within two hours; cetyl trimethylammonium bromide plus nitrite was not significantly hepatotoxic. 2.
Maduagwu, E. N.
core +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Smart worm-like micelles responsive to CO₂/N₂ and light dual stimuli [PDF]
CO₂/N₂ and light dual stimuli-reponsive worm-like micelles (WLMs) were obtained by addition of a relatively small amount of a switchable surfactant, 4-butyl-4´-(4-N,N-dimethylhexyloxy-amine) azobenzene bicarbonate (AZO-B6-CO₂), sensitive to the same ...
Binks, Bernard P. +4 more
core +1 more source
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Revisiting the Kinetics and Mechanism of Bromate-Bromide Reaction
The bromate-bromide reaction was investigated in an acidity range not studied yet. The reaction was followed at the Br2/Br3- isosbestic point (lambda = 446 nm).
Côrtes Carlos Eduardo S. +1 more
doaj
Investigating the effect of the simultaneous presence of bromide ions in the removal of dye from textile wastewater by the UV/Cl process [PDF]
Background and Objective: UV and chlorination processes are widely used for wastewater and water disinfection. In recent years, they have been used integrative under the name of Advance oxidation process (AOP) method known as UV/chlorine process.
Sobhan Ghanbari +3 more
doaj

