Bromotrimethylsilane as a selective reagent for the synthesis of bromohydrins. [PDF]
RSC Adv, 2021 Glycerol, a by-product of biodiesel production, can be efficiently converted into α-monobromohydrin or α,γ-dibromohydrin with trimethylsilyl bromide (TMSBr), in solvent-free and mild reaction conditions.
Giomi D +3 more
europepmc +4 more sources
Rational design, optimization, and biological evaluation of novel α-Phosphonopropionic acids as covalent inhibitors of Rab geranylgeranyl transferase. [PDF]
J Enzyme Inhib Med Chem, 2022 Rab geranylgeranyltransferase (GGTase-II, RGGT) catalyses the post-translational modification of eukaryotic Rab GTPases, proteins implicated in several pathologies, including cancer, diabetes, neurodegenerative, and infectious diseases.
Małolepsza J +6 more
europepmc +3 more sources
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. [PDF]
Viruses, 2022 Human norovirus is the first cause of foodborne disease worldwide, leading to extensive outbreaks of acute gastroenteritis, and causing around 200,000 children to die annually in developing countries.
Giancotti G +15 more
europepmc +6 more sources
Direct Synthesis of Bipyrroles Using Phenyliodine Bis(trifluoroacetate) with Bromotrimethylsilane. [PDF]
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Toshifumi, Dohi +3 more
openaire +2 more sources
THE REACTION OF TETRAMETHYLSILANE WITH BORON TRIBROMIDE [PDF]
, 2001 The reaction of tetramethylsilane with boron tribromide in deuterochloroform in ambient temperature or at 40°C led to bromotrimethylsilane (3) and to dibromomethylborane (4). Identity of products was confirmed by NMR spectroscopy.
Lewkowski, Jarosław, Vaultier, Michel
core +1 more source
Addition of Di(trimethylsilyl) Phosphite to Schiff Bases of 2,5-Diformylfuran [PDF]
, 2011 A series of 2,5-Furanyl-bis-(aminomethylphosphonic Acids) has been synthesized by the addition of di(trimethylsilyl) phosphite to azomethine bond of achiral Schiff bases derved from 2,5-diformylfuran.
Ciechańska, Magdalena +3 more
core +1 more source
Modular synthesis of biologically active phosphatidic acid probes using click chemistry [PDF]
, 2009 Phosphatidic acid (PA) is an important signaling lipid that plays roles in a range of biological processes including both physiological and pathophysiological events.
Best, Michael D. +4 more
core +1 more source
A Sustainable Improvement of ω-Bromoalkylphosphonates Synthesis to Access Novel KuQuinones [PDF]
, 2021 Owing to the attractiveness of organic phosphonic acids and esters in the pharmacological field and in the functionalization of conductive metal-oxides, the research of effective synthetic protocols is pivotal.
Conte, Valeria +4 more
core +1 more source
A bisphosphonate for F-19-magnetic resonance imaging [PDF]
, 2016 19F-magnetic resonance imaging (MRI) is a promising technique that may allow us to measure the concentration of exogenous fluorinated imaging probes quantitatively in vivo.
Botnar, RM +5 more
core +1 more source
Phosphonodifluoropyruvate is a mechanism-based inhibitor of phosphonopyruvate decarboxylase from Bacteroides fragilis [PDF]
, 2017 Bacteroides fragilis, a human pathogen, helps in the formation of intra-abdominal abscesses and is involved in 90% of anaerobic peritoneal infections.
Andrews, Forest H. +4 more
core +1 more source