Results 181 to 190 of about 5,063 (242)

In Vitro Evaluation of the Inhibitory Effects of Linarin on Histamine‐Induced Expression of Proinflammatory Cytokines, Mucin 5AC, and Aquaporin 5 in Human Nasal and Bronchial Epithelial Cells

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley   +1 more source

Clinical Outcomes in Patients With T4b Esophageal Squamous Cell Carcinoma: A 10‐Year Single Institution Experience

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) with adjacent structure invasion (T4b), affecting areas such as the aorta, vertebral body, or trachea, is associated with a poor prognosis, and the optimal treatment strategy remains unclear. While chemotherapy is considered standard, radiation therapy is often avoided due to the risk of severe ...
Yi‐Hsun Chen   +6 more
wiley   +1 more source

Oxymatrine Inhibits Epithelial‐Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF‐β1/Smad Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley   +1 more source

Feasibility of Treating Eosinophilic Chronic Rhinosinusitis Using Short‐Chain Fatty Acids

open access: yesThe Laryngoscope, EarlyView.
Epithelial cell‐derived cytokines including thymic stromal lymphopoietin (TSLP) are important in the pathogenesis of chronic rhinosinusitis with nasal polyps. We demonstrate the inhibitory effect of TSLP production in airway epithelial cells and eosinophil survival by short‐chain fatty acids (SCFAs) as a potential new strategy to reduce nasal polyps ...
Rikako Gozawa   +12 more
wiley   +1 more source

Biomedical Applications of 3D‐Printed Polyamide: A Systematic Review

open access: yesMacromolecular Materials and Engineering, EarlyView.
Additive manufacturing expands possibilities for personalized biomedical solutions, emphasizing the role of material science. This review examines the mechanical properties of 3D printed polyamide and explores its advantages and limitations in biomedical applications, including personalized implants, medical devices, and patient‐specific tools, as well,
Emese Paari‐Molnar   +12 more
wiley   +1 more source

Tumor Necrosis Factor‐α Induces Human Bronchial Fibroblasts to Produce Cytokines: Implications for Airway Inflammation

open access: yesMed Research, EarlyView.
ABSTRACT Pulmonary fibroblasts coordinate the progression of airway inflammation through multiple pathways. However, the role and underlying mechanisms of its subtype, bronchial fibroblasts, under TNF‐α induction remain unclear. This study found that TNF‐α was highly expressed in the airway with asthma patients.
Dong Zhang   +7 more
wiley   +1 more source

Global, Regional, and National Burden of Cancer in the Elderly Population, 1990–2021: Analysis of Data From the Global Burden of Disease Study 2021

open access: yesMed Research, EarlyView.
ABSTRACT With the global aging trend intensifying, cancer presents a significant health challenge for the elderly. This study aims to assess the prevalence, mortality, and disability‐adjusted life years (DALY) burden of cancer among individuals aged 60–94 worldwide from 1990 to 2021.
Xiaohan Zhu   +4 more
wiley   +1 more source

Relaxant effect of brain natriuretic peptide in nonsensitized and passively sensitized isolated human bronchi

open access: green, 2009
Maria Gabriella Matera   +5 more
openalex   +2 more sources

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