Results 41 to 50 of about 92,147 (287)
The importance of detailed epigenomic profiling of different cell types within organs. [PDF]
, 2016 The human body consists of hundreds of kinds of cells specified from a single genome overlaid with cell type-specific epigenetic information. Comprehensively profiling the body's distinct epigenetic landscapes will allow researchers to verify cell types ...
Borok, Zea +4 more
core +1 more source
Agreement Among Radiographs, Fluoroscopy and Bronchoscopy in Documentation of Airway Collapse in Dogs. [PDF]
, 2015 BackgroundAirway collapse is a common finding in dogs with chronic cough, yet the diagnosis can be difficult to confirm without specialty equipment.HypothesisBronchoscopic documentation of tracheobronchial collapse will show better agreement with ...
Johnson, LR, Pollard, RE, Singh, MK
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Diffuse pulmonary hemosiderosis after exposure to pesticides - A case report [PDF]
, 1998 This report describes the clinical, radiological, microscopical and ligandohistochemical findings in a 17-year-old woman who suffered from an acute onset of pulmonary hemosiderosis after inhalation of pesticides used for the cultivation of strawberries ...
Altiner, Mithat +5 more
core +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Combined Bronchoscopy in the Removal of a Long-standing Foreign Body of the Left Lower Lobe Bronchus
Неотложная медицинская помощь, 2019 The authors report a clinical observation of the removal of a large foreign body (a dental prosthesis with a sharp metal pin) of the left inferior bronchus with combined use of rigid and flexible bronchoscopy.
A. V. Mironov +4 more
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
A Rare Case of the Long Time Presence of a Half Meter Wire in Bronchus of a 38-Year-Old Patient
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014 Background and Objectives: Aspiration of foreign body into the bronchus is one the emergency problems, which emergency measures are required for its removal.
Abolfazl Mozaffari
doaj
Бюллетень сибирской медицины, 2007 Influence on mechanical tension of smooth muscles of isolated segments of bronchi of nitrosoglutathione and sodium nitroprusside on healthy and sensibilized guinea pigs by an ovalbumin was studied in conditions close to isometric, by a method of ...
Ye. Yu. Diyakova, K. V. Davletiyarova
doaj +1 more source