Results 41 to 50 of about 61,982 (308)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Contractile endothelin-B (ETB) receptors in human small bronchi
, 1996 Endothelins (ETs) are a family of novel regulatory peptides and various lines of evidence suggest an important role for ETs in regulating pulmonary function.
Cardell, Lars-Olaf +4 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Combined Bronchoscopy in the Removal of a Long-standing Foreign Body of the Left Lower Lobe Bronchus
Неотложная медицинская помощь, 2019 The authors report a clinical observation of the removal of a large foreign body (a dental prosthesis with a sharp metal pin) of the left inferior bronchus with combined use of rigid and flexible bronchoscopy.
A. V. Mironov +4 more
doaj +1 more source
Isovolume pressure-flow relationships in intrapulmonary bronchi of excised dog lungs
, 1982 From excised dog lungs we isolated airtight the intrapulmonary main bronchi (5–6 cm in length) with beads according to the technique described by Takishima et al. (J. Appl. Physiol.
K. Sekizawa +3 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah +8 more
wiley +1 more source
Бюллетень сибирской медицины, 2007 Influence on mechanical tension of smooth muscles of isolated segments of bronchi of nitrosoglutathione and sodium nitroprusside on healthy and sensibilized guinea pigs by an ovalbumin was studied in conditions close to isometric, by a method of ...
Ye. Yu. Diyakova, K. V. Davletiyarova
doaj +1 more source
Tracheobronchial Amyloidosis Accompanied with Asthma: A Case Report and a Mini-Review
Journal of Asthma and Allergy, 2023 Lina Sun,1,2,* Kexin Liu,1,2,* Meijiao Li,3 Yongchang Sun,1,2 Xiang Zhu,4,5 Chun Chang1,2 1Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, People’s Republic of China; 2Research Center for Chronic ...
Sun L +5 more
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