Results 81 to 90 of about 65,324 (305)

Usefulness of computed tomography virtual bronchoscopy in the evaluation of bronchi divisions

open access: yes, 2013
Background: Since introduction of multislice CT scanners into clinical practice, virtual brochoscopy has gained a lot of quality and diagnostic potential.
Adamczyk, Michał   +4 more
core   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

open access: yesAdvanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl   +20 more
wiley   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

open access: yesAdvanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu   +17 more
wiley   +1 more source

Non-Fibrotic Bronchi: Major Changes in Gene Expression.

open access: yes, 2015
aFold change relative to air-exposed controlsNon-Fibrotic Bronchi: Major Changes in Gene Expression.
Yu Wang (12152)   +10 more
core   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

open access: yesAdvanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang   +10 more
wiley   +1 more source

Combined Bronchoscopy in the Removal of a Long-standing Foreign Body of the Left Lower Lobe Bronchus

open access: yesНеотложная медицинская помощь, 2019
The authors report a clinical observation of the removal of a large foreign body (a dental prosthesis with a sharp metal pin) of the left inferior bronchus with combined use of rigid and flexible bronchoscopy.
A. V. Mironov   +4 more
doaj   +1 more source

Mechanical dissociation of bronchi from parenchyma in the immature piglet lung

open access: yes, 2000
Previous studies of isolated piglet lungs suggested that local distending forces around bronchi might be relatively weak before postnatal growth and maturation.
Allison L. McAteer   +2 more
core   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

open access: yesAdvanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang   +9 more
wiley   +1 more source

Tracheobronchial Amyloidosis Accompanied with Asthma: A Case Report and a Mini-Review

open access: yesJournal of Asthma and Allergy, 2023
Lina Sun,1,2,* Kexin Liu,1,2,* Meijiao Li,3 Yongchang Sun,1,2 Xiang Zhu,4,5 Chun Chang1,2 1Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, People’s Republic of China; 2Research Center for Chronic ...
Sun L   +5 more
doaj  

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