Results 131 to 140 of about 185,871 (286)

Progressive Pulmonary Alveolar Proteinosis Diagnosis Masking Pneumonic Lung Carcinoma: Anchoring Bias in Critical Care

open access: yesCytopathology, EarlyView.
A presumed case of pulmonary alveolar proteinosis with clinical deterioration was ultimately identified at autopsy as pneumonic‐type pleomorphic carcinoma. This case highlights the diagnostic overlap between diffuse lung diseases and the risk of anchoring bias in critically ill patients.
Dakota Wheeler   +3 more
wiley   +1 more source

Pattern‐based interpretation of SOX2 expression in ovarian teratomas: avoiding diagnostic pitfalls in the distinction between immature and mature neuroectodermal elements

open access: yesHistopathology, EarlyView.
Ovarian immature teratoma grading may be confounded by mature neuroectodermal mimics. SOX2 labelled immature neuroepithelium but also mature ependymal and glial tissue, while SALL4 was negative in mature mimics and variably expressed in immature neuroepithelium.
Agnese Orsatti   +14 more
wiley   +1 more source

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

open access: yesImmunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan   +5 more
wiley   +1 more source

Safety, feasibility, and usefulness of bronchoscopic thermal ablation techniques in the management of endobronchial neoplasms

open access: yesThe Egyptian Journal of Bronchology
Background A common sign of lung cancer is central involvement of the airway. Bronchoscopic electrocautery, laser, argon plasma coagulation (APC), cryotherapy, photodynamic therapy, brachytherapy, intra-tumoral chemotherapy, mechanical debridement, and ...
Sabah Ahmed Hussein   +5 more
doaj   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

open access: yesImmunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch   +3 more
wiley   +1 more source

Bronchial Neoplasm with Eosinophilia

open access: yesInternational Journal of Clinical Practice, 1981
openaire   +2 more sources

Survival outcomes in dogs treated with vinorelbine‐based adjuvant treatment following surgical resection of grade II and III pulmonary carcinoma

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives Pulmonary carcinoma in dogs is commonly managed with surgical resection; however, the role of adjuvant chemotherapy for grade II and III carcinomas remains unclear. This retrospective multicentre study investigated the outcomes in dogs treated with vinorelbine‐based adjuvant treatment (as monotherapy or combined chemotherapy) following ...
N. Wong, L. Brockley, S. Rajan, J. Yu
wiley   +1 more source

Cell Germ primary tumor of mediastinum (seminoma of mediastinum)

open access: yesArchivo Médico de Camagüey, 2019
Background: the anterior mediastinal germ cell tumor is a formation of neoplastic cells located in the mediastinum. They are formed by congenital defects in the embryonic stage by migration of the primordial germ cell and dermal cells that are within the
René Hernández-Benedicto   +2 more
doaj  

Bronchial carcinoid presenting with abdominal pain

open access: yes, 2005
Bronchial carcinoid tumors are very rare pulmonary neoplasms. They usually present with pulmonary symptoms or paraneoplastic syndromes. Typical (well-differentiated) tumors are usually indolent with survival exceeding 90% after resection.
Yaqoob, Nausheen   +4 more
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