Results 31 to 40 of about 42,470 (219)

Investigation and Analysis of the Current Status of Bronchial Provocation Testing in Guangdong Province [PDF]

Zhongguo quanke yixue
Background The prevalence of bronchial asthma has been rising annually, yet primary healthcare institutions still face difficulties in early diagnosis and treatment. Bronchial provocation test (BPT) is an important diagnostic tool with significant value.
WU Zhongping, ZHENG Jingping, GAO Yi, CHEN Xiaoliang
doaj   +1 more source

The sensitivity and specificity of the mannitol bronchial challenge test to identify asthma in different populations: a systematic review

Swiss Medical Weekly, 2019
OBJECTIVE Asthma is associated with bronchial hyperresponsiveness, assessed by bronchial provocation tests such as the mannitol test. We aimed to assess the data on sensitivity and specificity of the mannitol test in diagnosing asthma.
Philipp Kernen, Esther H. Steveling-Klein, Ramon T. Saccilotto, Heike Raatz, Matthias Briel, Michael T. Koller, Marie Westwood, Heiner C. Bucher, David Miedinger, Jörg D. Leuppi   +9 more
doaj   +1 more source

Effect of mannitol dry powder challenge on exhaled nitric oxide in children. [PDF]

PLoS ONE, 2013
BackgroundFractional exhaled nitric oxide (FENO), a non-invasive marker of eosinophilic airway inflammation, is increasingly used for diagnostic and therapeutic decisions in adult and paediatric asthma. Standardized guidelines for the measurement of FENO
Juerg Barben, Marie-Pierre F Strippoli, Daniel Trachsel, Barbara Schiller, Juerg Hammer, Claudia E Kuehni   +5 more
doaj   +1 more source

Work-related asthma

Jornal Brasileiro de Pneumologia, 2021
Work-related asthma (WRA) is highly prevalent in the adult population. WRA includes occupational asthma (OA), which is asthma caused by workplace exposures, and work-exacerbated asthma (WEA), also known as work-aggravated asthma, which is preexisting or ...
Lavinia Clara Del Roio, Rafael Futoshi Mizutani, Regina Carvalho Pinto, Mário Terra-Filho, Ubiratan Paula Santos   +4 more
doaj   +2 more sources

Increased lung deposition and biological effect of methacholine by use of a drying device for bronchial provocation tests.

European Respiratory Journal, 1991
A simple device aiming to increase deposition of nebulized methacholine in the lower airway was studied. The device controlled inspiratory flow and volume and dried the aerosol.
P. Malmberg, K. Larsson, S. Thunberg
semanticscholar   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Associations of AMP and adenosine induced dyspnea sensation to large and small airways dysfunction in asthma

BMC Pulmonary Medicine, 2019
Background Bronchial provocation is often used to confirm asthma. Dyspnea sensation, however, associates poorly with the evoked drop in FEV1. Provocation tests only use the large airways parameter FEV1, although dyspnea is associated with both large- and
Claire A. Cox, Ilse M. Boudewijn, Sebastiaan J. Vroegop, Siebrig Schokker, Anne J. Lexmond, Henderik W. Frijlink, Paul Hagedoorn, Judith M. Vonk, Martijn P. Farenhorst, Nick H. T. ten Hacken, Huib A. M. Kerstjens, Maarten van den Berge   +11 more
doaj   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

iNew Medicine, EarlyView.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng, Wenhui Zhao, Min Wang, Xianwen Wang   +3 more
wiley   +1 more source

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

Interdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar, Sunil Kumar Singh, Piush Srivastava, Sowdhamini Mahendiran, Rakesh Sathish Nair, Harsh Vyas, Saket Jha, Niraj Nag, Navin Viswakarma, Hitesh Kapoor, Swathi Suresh, Periannan Sethupathi, Sang‐Ging Ong, Jerrold S. Levine, Suman Setty, Mathayan Manikannan, Bellur S. Prabhakar, Basabi Rana, Ajay Rana   +18 more
wiley   +1 more source

When toothache results in asthma diagnosis

International Journal of Occupational Medicine and Environmental Health, 2021
Local anesthetics (LA) have been used for a wide variety of procedures over the years due to their analgesic effect. These drugs have been seen to cause adverse events in the pediatric population, but an actual allergy must be in question.
Maryam Rahimo, Joanna Jerzyńska, Agnieszka Brzozowska, Daniela Podlecka   +3 more
doaj   +1 more source