Results 31 to 40 of about 11,132 (205)

Hyaluronic Acid‐Decorated Liposomes for the Intrapulmonary Delivery of Imatinib: A Targeted Treatment for Postinflammatory Pulmonary Fibrosis

Small Science, EarlyView.
Hyaluronic acid‐decorated imatinib‐loaded liposomes are developed to specific target CD44 receptor expressed by interstitial lung fibrosis cells, demonstrating higher uptake than empty liposomes. Based on promising in vitro data, they are administered intratracheally and intraperitoneally in a mouse bleomycin model, assessing their ability to decrease ...
Sara Bozzini, Valeria Bincoletto, Laura Pandolfi, Roberta Fusco, Rosanna Di Paola, Salvatore Cuzzocrea, Ilaria Andreana, Barbara Rolando, Eleonora Bozza, Cecilia Bagnera, Manuela Monti, Barbara Stella, Federica Meloni, Silvia Arpicco   +13 more
wiley   +1 more source

Long‐term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium

British Journal of Haematology, EarlyView.
The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune, Florian Chevillon, Mony Fahd, Kristell Desseaux, Xavier Poiré, Edouard Forcade, Arthur Sterin, Bénédicte Neven, Virginie Gandemer, Sylvain Thepot, Alice Garnier, Bruno Lioure, Ambroise Marcais, Stephanie Nguyen‐Quoc, Suzanne Tavitian, Laure Vincent, Jean Donadieu, Matthieu Resche Riggon, Sylvie Chevret, Marlene Pasquet, Regis Peffault de Latour   +20 more
wiley   +1 more source

Protective effects of neutrophil serine protease inhibition against ischemia–reperfusion injury in lung or heart transplantation

The FEBS Journal, EarlyView.
A major complication of organ transplantation is primary graft dysfunction, which represents the leading cause of early post‐transplantation morbidity and mortality. Pre‐operative depletion of neutrophil serine proteases in circulating neutrophils by pretreatment with a cathepsin C inhibitor in recipients could prevent early post‐operative ...
Sevil Korkmaz‐Icöz, Gábor Szabó, Artur Gieldon, Patrick P. McDonald, Alexey Dashkevich, Ali Önder Yildirim, Brice Korkmaz   +6 more
wiley   +1 more source

Non-infectious respiratory complications after allogeneic bone marrow transplantation: single center experience in Egypt

The Egyptian Journal of Bronchology
Background Hematopoietic progenitor cells are infused intravenously, known as hematopoietic stem cell transplantation. The range of pulmonary problems after transplantation of hematopoietic stem cells varies significantly from infectious to non ...
Mona M. Motawea, Mohamed Abd Elmooti Samra, Salwa Atef Ganna, Basem Ibrahim Elshafey   +3 more
doaj   +1 more source

LTB4 and montelukast in transplantation-related bronchiolitis obliterans in rats

Journal of Cardiothoracic Surgery, 2017
Background Lung transplantation is the only effective treatment for end-stage lung diseases. Bronchiolitis obliterans, which is known as non-infectious chronic lung allograft dysfunction (CLAD) in the new classification, is the greatest threat to long ...
Zheng-Liang Tu, Zhen-Yu Zhou, Hai-Chao Xu, Jin-Lin Cao, Peng Ye, Lu-Ming Wang, Wang Lv, Jian Hu   +7 more
doaj   +1 more source

Simultaneous viral infection and childhood bronchiolitis obliterans

Brazilian Journal of Infectious Diseases, 2002
Lower respiratory tract infections by respiratory syncytial virus (RSV) are frequent in childhood. Association of RSV with bronchiolitis obliterans has rarely been established.
Hirschheimer Mário, Silva Paulo S. L., Giudici Roseli, Carrilho Milene, Mauad Thais, Ishida Maria   +5 more
doaj  

Histopathological Analogies in Chronic Pulmonary Lesions between Cattle and Humans: Basis for an Alternative Animal Model

The Scientific World Journal, 2012
Most of the natural cases of pneumonia in feedlot cattle are characterized by a longer clinical course due to chronic lung lesions. Microscopically, these lesions include interstitial fibroplasia, bronchitis, bronchiectasis, bronchiolitis obliterans, and
Rafael Ramírez-Romero, Alicia M. Nevárez-Garza, Luis E. Rodríguez-Tovar, Alfredo Wong-González, Rogelio A. Ledezma-Torres, Gustavo Hernández-Vidal   +5 more
doaj   +1 more source

Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation

Hematology Reports, 2013
Pneumothorax is very rare after early phase of hematopoietic stem cell transplantation (HSCT) and usually accompanied with pulmonary chronic graft-versus-host disease (GVHD), such as bronchiolitis obliterans and bronchiolitis obliterans organizing ...
Yasuhiro Ebihara, Shohei Yamamoto, Shinji Mochizuki, Masao Tsukada, Yuki Taya, Toshiro Kawakita, Seiko Kato, Jun Ooi, Satoshi Takahashi, Arinobu Tojo, Kohichiro Tsuji   +10 more
doaj   +1 more source

Bronchiolitis obliterans syndrome associated with an immune checkpoint inhibitor in a patient with non-small cell lung cancer

Respiratory Medicine Case Reports, 2023
A 75-year-old woman was admitted to our hospital with progressive dyspnea 7 months after second-line treatment with pembrolizumab for advanced non-small cell lung cancer.
Kenichiro Takeda, Hideki Miwa, Masato Kono, Ryutaro Hirama, Yuiko Oshima, Yasutaka Mochizuka, Akari Tsutsumi, Yoshihiro Miki, Dai Hashimoto, Hidenori Nakamura   +9 more
doaj  

Obliterative bronchiolitis in rheumatoid arthritis (clinical case)

Современная ревматология, 2023
Obliterative (constrictive) bronchiolitis (OB) is a rare disease characterized by destruction of the bronchiolar epithelium and subsequent progressive airway obstruction. OB is most common in rheumatoid arthritis (RA) compared to other systemic rheumatic
T. N. Petrachkova, I. N. Trofimenko, E. N. Dudina, A. O. Petrachkova, M. E. Kulkova   +4 more
doaj   +1 more source