Results 31 to 40 of about 11,234 (204)

Low‐dose versus high‐dose methylprednisolone for children with severe Mycoplasma pneumoniae pneumonia (MCMP): A randomized controlled trial

Pediatric Investigation, EarlyView.
Although macrolides combined with glucocorticoids can prevent long‐term pulmonary lesions by severe Mycoplasma pneumoniae pneumonia (MPP), evidence regarding glucocorticoid dose is lacking. We found that high‐dose methylprednisolone compared to low‐dose did not reduce long‐term pulmonary lesions of severe MPP in Chinese children, but significantly ...
Baoping Xu, Ling Cao, Yunxiao Shang, Liping Liu, Liwei Gao, Ju Yin, Jun Liu, Ruohua Yan, Bo Peng, Yong Feng, Zhiying Han, Yao Yao, Wenhui Guo, Nan Yang, Jie Chang, Yiqin Song, Hao Wang, Xirong Wu, Xinyu Wang, Ning Chen, Xiaojuan Zhang, He Zhang, Anxia Jiao, Adong Shen, Keqing Zhang, Yan Yang, John S. Ji, Xiaoxia Peng, Kunling Shen, MCMP study Group   +29 more
wiley   +1 more source

Bronchiolitis Obliterans (BO): HRCT findings in 20 patients

The Egyptian Journal of Radiology and Nuclear Medicine, 2014
Introduction: Bronchiolitis obliterans (BO), also known as constrictive bronchiolitis is a fibrosing form of obstructive lung disease that follows a severe insult to the lower respiratory tract.
Youssriah Yahia Sabri, Iman M. Hamdy Ibrahim, Adriana Fouad Radman   +2 more
doaj   +1 more source

Hyaluronic Acid‐Decorated Liposomes for the Intrapulmonary Delivery of Imatinib: A Targeted Treatment for Postinflammatory Pulmonary Fibrosis

Small Science, EarlyView.
Hyaluronic acid‐decorated imatinib‐loaded liposomes are developed to specific target CD44 receptor expressed by interstitial lung fibrosis cells, demonstrating higher uptake than empty liposomes. Based on promising in vitro data, they are administered intratracheally and intraperitoneally in a mouse bleomycin model, assessing their ability to decrease ...
Sara Bozzini, Valeria Bincoletto, Laura Pandolfi, Roberta Fusco, Rosanna Di Paola, Salvatore Cuzzocrea, Ilaria Andreana, Barbara Rolando, Eleonora Bozza, Cecilia Bagnera, Manuela Monti, Barbara Stella, Federica Meloni, Silvia Arpicco   +13 more
wiley   +1 more source

Younger Age and Viral Triggers Were Associated With Post‐Infectious Bronchiolitis Obliterans in French Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim Post‐infectious bronchiolitis obliterans (PIBO) is a rare but severe chronic paediatric obstructive lung disease, characterised by the obliteration of small airways following severe lower respiratory tract infections. Epidemiological data in Europe remain limited. Methods This multicentre retrospective study examined the characteristics of
Julie Mazenq, Marine Crebassa, Alice Hadchouel, Souad Ghattas, Philippe Reix, Laurianne Coutier, Christophe Marguet, Nadia Nathan, Lisa Giovannini‐Chami, Caroline Thumerelle, François Galode, Marie‐Catherine Renoux, Léa Roditis, Eglantine Hullo, Pierrick Cros, Laurence Weiss, Sébastien Kiefer, Marie Tochon, Brahim Allali, Katia Bessaci Kabouya, Céline Delestrain, Louisa Goumidi, Hortense Petat, Véronique Houdouin, Jean‐Christophe Dubus   +24 more
wiley   +1 more source

Long‐term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium

British Journal of Haematology, EarlyView.
The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune, Florian Chevillon, Mony Fahd, Kristell Desseaux, Xavier Poiré, Edouard Forcade, Arthur Sterin, Bénédicte Neven, Virginie Gandemer, Sylvain Thepot, Alice Garnier, Bruno Lioure, Ambroise Marcais, Stephanie Nguyen‐Quoc, Suzanne Tavitian, Laure Vincent, Jean Donadieu, Matthieu Resche Riggon, Sylvie Chevret, Marlene Pasquet, Regis Peffault de Latour   +20 more
wiley   +1 more source

Protective effects of neutrophil serine protease inhibition against ischemia–reperfusion injury in lung or heart transplantation

The FEBS Journal, EarlyView.
A major complication of organ transplantation is primary graft dysfunction, which represents the leading cause of early post‐transplantation morbidity and mortality. Pre‐operative depletion of neutrophil serine proteases in circulating neutrophils by pretreatment with a cathepsin C inhibitor in recipients could prevent early post‐operative ...
Sevil Korkmaz‐Icöz, Gábor Szabó, Artur Gieldon, Patrick P. McDonald, Alexey Dashkevich, Ali Önder Yildirim, Brice Korkmaz   +6 more
wiley   +1 more source

Non-infectious respiratory complications after allogeneic bone marrow transplantation: single center experience in Egypt

The Egyptian Journal of Bronchology
Background Hematopoietic progenitor cells are infused intravenously, known as hematopoietic stem cell transplantation. The range of pulmonary problems after transplantation of hematopoietic stem cells varies significantly from infectious to non ...
Mona M. Motawea, Mohamed Abd Elmooti Samra, Salwa Atef Ganna, Basem Ibrahim Elshafey   +3 more
doaj   +1 more source

Histopathological Analogies in Chronic Pulmonary Lesions between Cattle and Humans: Basis for an Alternative Animal Model

The Scientific World Journal, 2012
Most of the natural cases of pneumonia in feedlot cattle are characterized by a longer clinical course due to chronic lung lesions. Microscopically, these lesions include interstitial fibroplasia, bronchitis, bronchiectasis, bronchiolitis obliterans, and
Rafael Ramírez-Romero, Alicia M. Nevárez-Garza, Luis E. Rodríguez-Tovar, Alfredo Wong-González, Rogelio A. Ledezma-Torres, Gustavo Hernández-Vidal   +5 more
doaj   +1 more source

LTB4 and montelukast in transplantation-related bronchiolitis obliterans in rats

Journal of Cardiothoracic Surgery, 2017
Background Lung transplantation is the only effective treatment for end-stage lung diseases. Bronchiolitis obliterans, which is known as non-infectious chronic lung allograft dysfunction (CLAD) in the new classification, is the greatest threat to long ...
Zheng-Liang Tu, Zhen-Yu Zhou, Hai-Chao Xu, Jin-Lin Cao, Peng Ye, Lu-Ming Wang, Wang Lv, Jian Hu   +7 more
doaj   +1 more source

Respiratory Viruses at Time of Lung Transplant and the Relationship to Primary Graft Dysfunction

Transplant Infectious Disease, EarlyView.
Primary graft dysfunction (PGD) is a form of severe and immediate post‐transplant lung injury that can lead to death. In our cohort of 229 patients undergoing lung transplantation with protocolized day 1 bronchoscopy specimens sent for respiratory viruses (RVs), RV+ status was not associated with an adjusted difference in the risk of PGD.
Laura van den Bosch, Karina Kaur, Rhea Varughese, Alim Hirji, Jason Weatherald, Justin Weinkauf, Dale Lien, Oscar Fernandez Garcia, Carlos Cervera Alvarez, Karen Doucette, Dima Kabbani, Kieran Halloran   +11 more
wiley   +1 more source