Results 121 to 130 of about 97,164 (250)

Clinical Impact of Maximum Plasma Concentration of Busulfan in Pediatric Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 702-712, September 2026.
Busulfan's narrow therapeutic index and high pharmacokinetic (PK) variability warrant investigation of its exposure–toxicity relationship. We retrospectively analyzed 334 pediatric and young adult patients who underwent allogeneic hematopoietic stem cell transplantation at Seoul National University Children's Hospital between 2009 and 2020 and received
Sungyeun Bae   +7 more
wiley   +1 more source

Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages

open access: yesJournal of Applied Toxicology, Volume 46, Issue 9, Page 3220-3231, September 2026.
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini   +4 more
wiley   +1 more source

Artificial intelligence‐enabled cytopathological interpretation of fluorescence microscopy images via a multimodal large language model

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Quantitative analysis of fluorescence microscopy images remains a significant challenge in cytopathological assessments, as subjective interpretation and inter‐observer variability hinder reproducibility and standardization of classifications. In this study, an artificial intelligence‐assisted analytical framework utilizing a multimodal large ...
Atakan Tevlek   +2 more
wiley   +1 more source

Hamman's crunch—A pathognomonic sign of pneumomediastinum

open access: yesEquine Veterinary Education, Volume 38, Issue 9, Page e571-e576, September 2026.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh   +4 more
wiley   +1 more source

Field‐applicable low‐intensity exercise induces bronchodilation in horses with severe asthma

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1445-1453, September 2026.
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Sophie Mainguy‐Seers   +2 more
wiley   +1 more source

Association of bronchoalveolar lavage cellular analysis and radiological findings in fibrotic interstitial lung diseases. [PDF]

open access: yesBMJ Open Respir Res
Kaenmuang P   +22 more
europepmc   +1 more source

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