Results 151 to 160 of about 97,164 (250)

Single-cell transcriptomics of bronchoalveolar lavage reveals divergent macrophage subpopulations and trajectories in interstitial lung disease. [PDF]

open access: yesPLoS One
Zhang LY   +12 more
europepmc   +1 more source

Targeting Elastin‐Derived Peptides Reverses Alveolar Epithelial Dysfunction in Chronic Obstructive Pulmonary Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
In COPD, extracellular matrix and elastin degradation increase elastin‐derived peptides (EDPs), which are associated with TLR4/NF‐κB activation, DKK1 upregulation, reduced β‐catenin signaling, and impaired AT2‐to‐AT1 differentiation. Neutralization of EDPs by TB partially restores β‐catenin‐associated alveolar epithelial differentiation and attenuates ...
Huijuan Zhu   +14 more
wiley   +1 more source

Lower Respiratory Microbiome Dysbiosis Is Associated With Poor Prognosis in Acute Severe Lower Respiratory Tract Infection

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Acute severe lower respiratory tract infection (asLRTI) present lower alpha‐diversity in lower respiratory tract microbiome (LRTM). Five clusters (C1–C5) were grouped, and cluster C3 was strongly associated with poor prognosis and reduced survival.
Minghua Zhan   +6 more
wiley   +1 more source

Cathepsin B, Airway Pathogens, and Inflammation in the Lower Airways of Children With Cystic Fibrosis

open access: yesPediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Introduction Dysregulated protease activity contributes to airway inflammation and tissue remodeling in cystic fibrosis (CF); however, the role of the lysosomal cysteine protease Cathepsin B (CTSB) remains incompletely defined. This cross‐sectional study investigates relationships between pro‐CTSB and mature CTSB activity with CF‐specific ...
Matthew K. Fought   +5 more
wiley   +1 more source

Muddy Water Pneumonitis: An Emerging Occupational Lung Disease in Professional Divers

open access: yesRespirology Case Reports, Volume 14, Issue 8, August 2026.
Chronic exposure to sediment‐rich river water in a professional diver led to progressive necrotizing lung injury mimicking tuberculosis. Bronchoalveolar lavage revealed Acinetobacter, highlighting a rare occupational cause of cavitary pneumonitis.
Sadia Sultana Resma   +3 more
wiley   +1 more source

Rapid Progressive Dendriform Pulmonary Ossification due to Eosinophilic Pneumonia

open access: yesRespirology Case Reports, Volume 14, Issue 8, August 2026.
A 55‐year‐old man with idiopathic eosinophilic pneumonia developed rapidly progressive dendriform pulmonary ossification with branching pulmonary calcifications on CT. Corticosteroid treatment improved both pulmonary consolidations and calcified lesions, suggesting that acute or immature pulmonary calcification may be reversible. ABSTRACT A 55‐year‐old
Koharu Harada   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy