Results 151 to 160 of about 100,703 (254)

Matrix Metalloproteinase‐8 Deficiency Alters the Balance Between Viral Clearance and Immunopathology in H1N1 Infection

open access: yesThe FASEB Journal, Volume 40, Issue 19, 15 October 2026.
Mmp‐8 deficiency during H1N1 influenza infection enhances Type I interferon responses, necroptosis‐associated signaling, and adaptive immunity, leading to lower lung viral burden and improved survival, but also amplifies inflammatory lung injury. ABSTRACT Matrix metalloproteinase‐8 (MMP‐8) regulates inflammatory responses, but its contributions to the ...
Xiaoyun Wang   +4 more
wiley   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou   +11 more
wiley   +1 more source

Torque Teno Virus in Bronchoalveolar Lavage Fluid of Hematological Patients and Association With Pathogens. [PDF]

open access: yesJ Med Virol
Ouafi M   +15 more
europepmc   +1 more source

What Is Your Diagnosis? Bronchoalveolar Lavage From a Cat

open access: yes
Veterinary Clinical Pathology, EarlyView.
Lina C. Bilhalva   +5 more
wiley   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt   +16 more
wiley   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang   +15 more
wiley   +1 more source

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