Results 71 to 80 of about 148,427 (325)

Inhalable Polymeric Nanoparticle Containing Triphenylphosphanium Bromide‐modified Sonosensitizer for Enhanced Therapy of Acute Bacterial Pneumonia

open access: yesAdvanced Science, EarlyView.
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang   +6 more
wiley   +1 more source

気管支喘息患者の血清コーチゾール値について. 副腎皮質ホルモン投与および年齢との関連 [PDF]

open access: yes, 1995
Serum cortisol levels were examined in 94 patients with bronchial asthma in relation to dose of glucocorticoids and age. 1. The level of serum cortisol was significantly lower in group A patients, treated with glucocorticoids (prednisolone of 5mg/day or ...
Harada, Hideo   +9 more
core   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

The evaluation of next‐generation sequencing assisted pathogenic detection in immunocompromised hosts with pulmonary infection: A retrospective study

open access: yesThe Clinical Respiratory Journal, Volume 16, Issue 12, Page 793-801, December 2022., 2022
In this study, we discovered that next‐generation sequencing (NGS)‐assisted pathogenic detection may improve detection efficiency and is associated with better clinical outcomes in immunocompromised pulmonary‐infected patients with radiographic evidence of bilateral diffuse lesions.
Donghui Zhang   +11 more
wiley   +1 more source

AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid. [PDF]

open access: yes, 2007
BACKGROUND: Surfactant protein D (SP-D) and Mannose Binding Lectin (MBL) are collectins that have opsonic and immunoregulatory functions, are found in lung fluid and interact with the human immunodeficiency virus (HIV).
French, Neil   +3 more
core   +2 more sources

Silicosarcoidosis: Histologic and Clinical Features of an Occupational Granulomatous Disease

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Sarcoidosis is a multisystem inflammatory disease of unknown etiology. Growing evidence indicates that occupational exposure to respirable crystalline silica (RCS) is associated with an increased incidence of sarcoidosis. Yet a diagnosis of sarcoidosis rarely prompts investigation to identify preventable exposures.
Jeremy T. Hua   +11 more
wiley   +1 more source

Features of transbronchial lung cryobiopsy‐diagnosed fibrotic hypersensitivity pneumonitis

open access: yesThe Clinical Respiratory Journal, Volume 17, Issue 1, Page 50-58, January 2023., 2023
This study describes the clinical and pathological features of fibrotic hypersensitivity pneumonitis diagnosed with transbronchial lung crybiopsy. Usual interstitial pneumonia was the most frequent pathological finding of fibrotic hypersensitivity pneumonitis.
Xi Zhan   +14 more
wiley   +1 more source

Androgens augment pulmonary responses to ozone in mice

open access: yesPhysiological Reports, 2019
Ozone causes airway hyperresponsiveness, a defining feature of asthma, and is an asthma trigger. In mice, ozone‐induced airway hyperresponsiveness is greater in males than in females, suggesting a role for sex hormones in the response to ozone.
Ross S. Osgood   +4 more
doaj   +1 more source

Outcomes Bronchoscopic Evaluation in A University Hospital

open access: yesJournal of Nepal Medical Association, 2016
Introduction: Study of clinical profile of the patients and diagnostic yield of the selected bronchoscopic procedures gives us important information in clinical decision making and better patient care.
Ram Hari Ghimire   +5 more
doaj   +3 more sources

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai   +8 more
wiley   +1 more source

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