Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation [PDF]
Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine, have positive effects on mouse models of human cystic fibrosis (CF). These measures
Amin R +39 more
core +4 more sources
Advances in miRNA research: Unraveling the complexities of gene regulation
Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
wiley +1 more source
Pulmonary sequestration: An uncommon presentation with acute chest pain
This is a case of 18-year-old teenager presented with acute left sided chest pain for five days. This was associated with intermittent cough, and loss of weight in two weeks.
Nur Syazwani Jamhuri +3 more
doaj +1 more source
Pulmonary sequestration - a case report and review of the litterature [PDF]
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenPulmonary sequestration is an uncommon congenital malformation where non-functioning lung tissue is separated from the normal bronchopulmonary tree and ...
Erik Gyllsted +2 more
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Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. [PDF]
The vascular endothelium is critical for induction of appropriate lineage differentiation in organogenesis. In this study, we report that dysfunctional pulmonary endothelium, resulting from the loss of matrix Gla protein (MGP), causes ectopic hepatic ...
Blazquez-Medela, Ana M +9 more
core +2 more sources
Neonatological and pulmonological management of bilateral pulmonary sequestration in a neonate [PDF]
Background: Bronchopulmonary sequestration is a lung malformation characterized by nonfunctioning lung tissue without primary communication with the tracheobronchial tree.
Nelle, Mathias +3 more
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Differential recognition of the Multiple Banded Antigen isoforms across Ureaplasma parvum and Ureaplasma urealyticum species by monoclonal antibodies [PDF]
Two separate species of Ureaplasma have been identified that infect humans: Ureaplasma parvum and Ureaplasma urealyticum. Most notably, these bacteria lack a cell wall and are the leading infectious organism associated with infection-related induction of
Aboklaish, Ali +5 more
core +2 more sources
Respiratory syncytial virus (RSV) causes substantial global morbidity, particularly in infants and elderly populations. This review summarizes key viral pathogenesis mechanisms and highlights recent advances in both prophylactic (vaccines, antibodies) and therapeutic (antiviral agents) strategies against RSV.
Xiaowen Liang +7 more
wiley +1 more source
Left Sided Oesophageal Lung: A Diagnostic Challenge
Bronchopulmonary foregut malformations (BPFMs) include a wide variety of malformations such as intralobar or extralobar pulmonary sequestration, foregut duplication cysts, and diverticula of the gastrointestinal or pulmonary tree (Srikanth et al., 1992).
Amitava Sur +2 more
doaj +1 more source
Pulmonary sequestration: a review of 26 cases [PDF]
Objectives: Pulmonary sequestration is a continuum of lung anomalies for which no single embryonic hypothesis is yet available. The aim of this study was to assess the diagnostic tools and treatment for the rare condition, pulmonary sequestration, in an ...
Boumghar, M. +4 more
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