Results 211 to 220 of about 420,571 (273)

221113 - Facility Water Distribution Piping [PDF]

, 2015
Weatherbee, Stephanie
core   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Revealing Ancient Wheat Phylogenetic Diversity: Machine Learning and Logistic Regression Identify <i>Triticum sphaerococcum</i> in Bronze Age Iberia. [PDF]

Genes (Basel)
Rivera D, Ros-Sala M, Rivera-Obón DJ, Alcaraz F, Ferrer-Gallego PP, Laguna E, Goncharov NP, Kruchinina YV, Obón C.   +8 more
europepmc   +1 more source

Memristive Baffle Systems: Design, Simulation, and Applications

Advanced Science, EarlyView.
This study presents a nanoscale baffle‐system strategy for HfO2‐based memristors that controls oxygen‐vacancy transport through Al2O3 interlayers. Guided by multiscale simulation and experimental validation, the Al2O3 dual‐barrier configuration simultaneously enhances synaptic linearity and endurance.
Eun Young Kim, Juseong Park, Sumin Ju, Taeyoung Jeong, Dohyun Kim, Woojoon Park, Myeongchan Ko, Woon Hyung Cheong, Jung‐Hae Choi, Kyung Min Kim   +9 more
wiley   +1 more source

Genetic affinities between the ancient Greek colony of Amvrakia and its metropolis. [PDF]

Genome Biol
Psonis N, Tabakaki E, Vassou D, Papadantonakis S, Souleles A, Nafplioti A, Kousis Tsampazis G, Papadopoulou A, Xanthopoulos K, Panailidis P, Georgiadou A, Papakosta D, Koursioti S, Evangelinou M, Papadopoulou V, Evaggeloglou P, Korka E, Christidis I, Ioannou M, Kontogianni T, Arkoumanis A, Stamatakis A, Poulakakis N, Papageorgopoulou C, Pavlidis P.   +24 more
europepmc   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, EarlyView.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

Correction: Emergence of monopoly-Copper exchange networks during the Late Bronze Age in the western and central Balkans. [PDF]

PLoS One
Gavranović M, Mehofer M, Kapuran A, Koledin J, Mitrović J, Papazovska A, Pravidur A, Đorđević A, Jacanović D.   +8 more
europepmc   +1 more source

Interfacially Reinforced Crosslinked Binder with Structural Integrity for Stable Micro‐Sized Silicon Anodes in All‐solid‐state Batteries

Advanced Science, EarlyView.
ABSTRACT All‐solid‐state batteries (ASSBs) have attracted considerable attention as next‐generation energy storage systems owing to their high energy density and safety. However, their performance is critically limited by insufficient solid–solid interfacial contact and severe chemomechanical degradation, particularly for micro‐sized silicon (µSi ...
Chanho Lee, Yuri Nam, Incheol Jeong, Seo Eun Lee, Taewook Kim, Jinhyung Kim, Wooseup Jo, Moonsu Yoon, Jongkyeong Lim, Seho Sun, Junghyun Choi, Chan Ho Park, Dongsoo Lee   +12 more
wiley   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Effect of Corrosion-Induced Damage on Fatigue Behavior Degradation of ZCuAl₈Mn₁₃Fe₃Ni₂ Nickel-Aluminum Bronze Under Accelerated Conditions. [PDF]

Materials (Basel)
Zhang R, Wang J, Wei P, Wang L, Huang C, Dai Z, Zhang J, Chen C, Guo X.   +8 more
europepmc   +1 more source