Results 91 to 100 of about 244,586 (299)
Advanced Science, EarlyView.The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang +7 more
wiley +1 more source
EXARC Journal, 2014 In spite of the very large quantity of Bronze Age swords in Northern Italy, only a few stone moulds have been found. Tests have shown that carving such big stone moulds (more than 60 cm long) requires a large amount of raw material, deep knowledge and ...
Luca Pellegrini, Federico Scacchetti
doaj
Revue Archéologique de l’Est, 2008 An evaluation carried out in 2003 at Malay-le-Grand « Les Bas Musats » (Yonne) brought to light a pit with rich finds dating from the middle period of the Late Bronze Age.
Fabrice Muller +2 more
doaj +1 more source
Advanced Science, EarlyView.GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang +12 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
The Bronze Casting Festival at the Bronzezeithof, Uelsen, Germany
EXARC Journal, 2017 The first Bronze Casting Festival was held in May 2017 at the Bronzezeithof in Uelsen, Germany. The event was organised by Martijn van Es, who has an active interest in bronze casting and experimental archaeology.
E. Giovanna Fregni
doaj
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Archaeological Evidence for an Early Second Millennium BC Potter’s Kiln at Liman Tepe
Belleten, 2016 This article will focus on a pottery kiln which is dated to the transition phase between the Early Bronze Age and the Middle Bronze Age in Liman Tepe.
Ayşegül Aykurt, Hayat Erkanal
doaj +1 more source
Towards a fuller, more nuanced narrative of Chalcolithic and Early Bronze Age Britain 2500-1500 BC [PDF]
, 2008 This contribution considers some of the many recent advances in our understanding of Chalcolithic and Bronze Age Britain and uses these to highlight the weak points in our current state of knowledge.
Sheridan, J A
core
Advanced Science, EarlyView.This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma +16 more
wiley +1 more source