Lepromatous leprosy in Bronze Age Oman: micro-CT provides tools for paleopathology in fragmentary and commingled assemblages. [PDF]
Robbins Schug G +6 more
europepmc +1 more source
Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar +2 more
wiley +1 more source
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
A Preliminary Survey of the Birds from Velikent (Bronze Age, Daghestan, Russia)
Arturo Morales Muñiz +1 more
openalex +2 more sources
Corrigendum to "Isotopic insights from carpological remains: One of the first datasets for the Italian Bronze age" [Data in brief 57 (2024) 111000]. [PDF]
Cortese F +10 more
europepmc +1 more source
Objectives The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS syndrome. Methods This multicenter international study includes VEXAS patients from France, Israel, and Italy treated with IL1 inhibition (IL1i).
Tali Eviatar +35 more
wiley +1 more source
Radiocarbon chronology and settlement patterns in the Bronze Age of the Qaidam Basin, Northwestern China. [PDF]
Li B +8 more
europepmc +1 more source
Diagnostic implications and correlates of plasma ADA2 activity and ADA2 variants
Objectives Deficiency of adenosine deaminase 2 (DADA2) is a monogenic autoinflammatory disease manifested as polyarteritis nodosa, stroke, and bone marrow failure. Leveraging an international cohort of 200 DADA2 cases, we aimed to characterize the diagnostic utility of a plasma ADA2 enzyme activity assay and understand the implications of residual ADA2
Jian Yue +55 more
wiley +1 more source
The excavation of a Neolithic, Bronze Age and Early Historic features near Ratho, Edinburgh
Andrea Smith +10 more
openalex +2 more sources
Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify non‐invasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin +11 more
wiley +1 more source

