Results 221 to 230 of about 251,830 (289)

Lepromatous leprosy in Bronze Age Oman: micro-CT provides tools for paleopathology in fragmentary and commingled assemblages. [PDF]

open access: yesFront Med (Lausanne)
Robbins Schug G   +6 more
europepmc   +1 more source

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar   +2 more
wiley   +1 more source

A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane   +33 more
wiley   +1 more source

Corrigendum to "Isotopic insights from carpological remains: One of the first datasets for the Italian Bronze age" [Data in brief 57 (2024) 111000]. [PDF]

open access: yesData Brief
Cortese F   +10 more
europepmc   +1 more source

Comparative efficacy and safety of anakinra and canakinumab in patients with VEXAS syndrome – an international multicenter study

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS syndrome. Methods This multicenter international study includes VEXAS patients from France, Israel, and Italy treated with IL1 inhibition (IL1i).
Tali Eviatar   +35 more
wiley   +1 more source

Diagnostic implications and correlates of plasma ADA2 activity and ADA2 variants

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Deficiency of adenosine deaminase 2 (DADA2) is a monogenic autoinflammatory disease manifested as polyarteritis nodosa, stroke, and bone marrow failure. Leveraging an international cohort of 200 DADA2 cases, we aimed to characterize the diagnostic utility of a plasma ADA2 enzyme activity assay and understand the implications of residual ADA2
Jian Yue   +55 more
wiley   +1 more source

The excavation of a Neolithic, Bronze Age and Early Historic features near Ratho, Edinburgh

open access: bronze, 1996
Andrea Smith   +10 more
openalex   +2 more sources

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify non‐invasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin   +11 more
wiley   +1 more source

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