Results 21 to 30 of about 46,567 (239)

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Development and Validation of a One‐Dimensional Finite Difference Simulation Scheme for Polymer Laser Powder Bed Fusion with Application to the Effect of the Inter Layer Time

open access: yesAdvanced Engineering Materials, EarlyView.
The study presents an efficient simulation approach for the polymer laser powder bed fusion process polymers process, validated with polyamide 12, polyamide 6, and polyetherketoneketone. It shows that inter layer time affects part density, with 90s yielding dense parts.
Claas Bierwisch   +4 more
wiley   +1 more source

Scalable Fabrication of Height‐Variable Microstructures with a Revised Wetting Model

open access: yesAdvanced Engineering Materials, EarlyView.
Height‐variable microstructures are fabricated using a scalable CO2 laser machining approach, enabling precise control of wettability through structural gradients. Classical wetting models fail to capture height‐induced effects, necessitating a revised theoretical framework.
Prabuddha De Saram   +2 more
wiley   +1 more source

Programmable Liquid Crystal Elastomers Via Magnetic Field Assisted Oligomerization

open access: yesAdvanced Functional Materials, EarlyView.
This article presents a straightforward method for designing programmable liquid crystal elastomer (LCE) actuators using magnetic field alignment. It combines thio‐Michael polyaddition for efficient LCE synthesis with a strategy that preserves the nematic phase, enabling the alignment of high molecular weight LCOs.
Rakine Mouhoubi   +2 more
wiley   +1 more source

Extracellular Matrix‐Mediated Crosslinking of Adhesive Hyaluronic Acid Patch for Treating Volumetric Muscle Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports a novel strategy for preparing a biocompatible adhesive hydrogel crosslinked with a muscle tissue‐derived extracellular matrix (MEM) for in situ muscle regeneration. As a natural crosslinker, MEM not only mediates combinatorial polymer networks but also stimulates satellite cells to induce a cell‐free therapeutic solution.
Eun Je Jeon   +6 more
wiley   +1 more source

Identification of histological threshold concepts in health sciences curricula: Students' perception

open access: yesAnatomical Sciences Education, Volume 16, Issue 1, Page 171-182, January/February 2023., 2023
Abstract Students' metacognitive skills and perceptions are considered important variables for high‐quality learning. In this study, students' perceptions were used to identify histological threshold concepts (integrative, irreversible, transformative, and troublesome) in three health sciences curricula.
Miguel A. Martin‐Piedra   +9 more
wiley   +1 more source

Recent Advances in Wide‐Bandgap Perovskite Solar Cells

open access: yesAdvanced Materials, EarlyView.
Ubiquitous defects predominately account for photo‐instability and open‐circuit voltage losses in wide‐bandgap perovskite solar cells (WBG PSCs). This review comprehensively presents the underlying impact mechanisms, summarizes the advanced optimization strategies across various functional layers and their interfaces to develop efficient and stable WBG
Jianjun Mei, Feng Yan
wiley   +1 more source

How Asian slum emissions impact local microclimates in polluted air masses

open access: yesAtmospheric Science Letters, Volume 23, Issue 12, December 2022., 2022
Cook stove emissions over urban sprawl in South India and expected microphysical implications. Combustion‐mediated soot and black carbon from biomass burning in shantytowns modulate the local cloud cover. Abstract Urban sprawl comprising densely populated slums over South Asian cities yields copious amounts of soot and black carbon from archaic cooking
Satyajit Ghosh   +4 more
wiley   +1 more source

Stress Response of Aspergillus niger Spores to Copper Surfaces and the Implications for Antifungal Surface Functionalization

open access: yesAdvanced Materials Interfaces, EarlyView.
This study investigates the antifungal efficacy of ultrashort pulsed laser‐induced periodic surface structures (USP‐DLIP) on copper, brass, and steel surfaces. Using Aspergillus niger as a model, the research highlights a 99% reduction in spore viability on 9 µm structured copper surfaces due to enhanced copper ion release. Scanning electron microscopy
Stella Marie Timofeev   +10 more
wiley   +1 more source

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