Results 41 to 50 of about 56,629 (301)

Phylogeography, genetic diversity, and connectivity of brown bear populations in Central Asia.

open access: yesPLoS ONE, 2019
Knowledge of genetic diversity and population structure is critical for conservation and management planning at the population level within a species' range.
Odbayar Tumendemberel   +11 more
doaj   +1 more source

The king of the forest: Local knowledge about European brown bears (Ursus arctos) and implications for their conservation in contemporary Western Macedonia

open access: yesConservation & Society, 2011
From a conservation point of view, Macedonia′s brown bear (Ursus arctos) population appears to be a key link in the distribution of one of Europe′s largest brown bear populations, the Dinaric-Pindos population. The lack of information concerning the bear
Nicolas Lescureux   +6 more
doaj   +1 more source

Integrating emotional affect into bear viewing management and bear safety education

open access: yesEcology and Society, 2021
The popularity of viewing wildlife, specifically brown bears (Ursus arctos), is increasing rapidly throughout North America. In addition, population distributions of both humans and brown bears are expanding, creating larger areas of overlap and an ...
John M. Nettles   +4 more
doaj   +1 more source

Partial genomic survival of cave bears in living brown bears [PDF]

open access: yesNature Ecology & Evolution, 2018
Although many large mammal species went extinct at the end of the Pleistocene epoch, their DNA may persist due to past episodes of interspecies admixture. However, direct empirical evidence of the persistence of ancient alleles remains scarce. Here, we present multifold coverage genomic data from four Late Pleistocene cave bears (Ursus spelaeus complex)
Barlow, Axel   +22 more
openaire   +8 more sources

Intrinsic and extrinsic factors influence on an omnivore's gut microbiome.

open access: yesPLoS ONE, 2022
Gut microbiomes (GMBs), complex communities of microorganisms inhabiting the gastrointestinal tracts of their hosts, perform countless micro-ecosystem services such as facilitating energy uptake and modulating immune responses.
Sarah M Trujillo   +9 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Nutrient intake and its possible drivers in free‐ranging European brown bears (Ursus arctos arctos)

open access: yesEcology and Evolution, 2023
The dietary nutrient profile has metabolic significance and possibly contributes to species' foraging behavior. The brown bear (Ursus arctos) was used as a model species for which dietary ingredient and nutrient concentrations as well as nutrient ratios ...
Annelies De Cuyper   +7 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Temporomandibular Joint Pathology of Wild Carnivores in the Western USA

open access: yesFrontiers in Veterinary Science, 2021
Skull specimens from: southern sea otter (Enhydra lutris nereis), Eastern Pacific harbor seal (Phoca vitulina), California sea lion (Zalophus californianus), northern fur seal (Callorhinus ursinus), walrus (Odobenus rosmarus), polar bear (Ursus maritimus)
Siobhan S. Rickert   +2 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

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