Results 101 to 110 of about 4,305,734 (370)

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants. [PDF]

, 2013
A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this finding has been replicated in case-control studies worldwide. In order to identify biologic factors at this
Ash, Colleen, Beck, Timothy, Bielecki, Ryszard, Boutros, Paul C, Chan-Seng-Yue, Michelle, Chong, Taryne, D'Souza, David JA, De Borja, Richard, Dick, John E, Gallinger, Steven, Gryfe, Robert, Hodgson, Lyndsey, Hudson, Thomas J, Kozak, Krystian, Kwan, Jennifer YY, Lee, Shawna, Lemire, Mathieu, McPherson, John D, Peltekova, Vanya D, Pollett, Aaron, Qazi, Aamer M, Rangrej, Jagadish, Rogers, Marianne, Stein, Lincoln D, Timms, Lee, Trinh, Quang M, Volar, Milica, Wang, Jianxin, Wang, Mike, Zaidi, Syed HE, Zandi, Sasan, Zanke, Brent W   +31 more
core   +2 more sources

Brown Tumor of the Thoracic Spine: First Manifestation of Primary Hyperparathyroidism

Journal of Korean Neurosurgical Society, 2015
Brown tumors also called as osteoclastomas, are rare nonneoplastic lesions that arise in the setting of primary or secondary hyperparathyroidism. Parathyroid adenomas or hyperplasia constitute the major Brown tumor source in primary hyperparathyroidism ...
Erkin Sonmez, T. Tezcaner, Ilker Coven, A. Terzi   +3 more
semanticscholar   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Sequential 3D U-Nets for Biologically-Informed Brain Tumor Segmentation [PDF]

arXiv, 2017
Deep learning has quickly become the weapon of choice for brain lesion segmentation. However, few existing algorithms pre-configure any biological context of their chosen segmentation tissues, and instead rely on the neural network's optimizer to develop such associations de novo.
arxiv  

Brown Tumor of the Patella Caused by Primary Hyperparathyroidism: A Case Report

Korean Journal of Radiology, 2015
It has been reported that the common sites of brown tumors are the jaw, pelvis, ribs, femurs and clavicles. We report our experience in a case of brown tumor of the patella caused by primary hyperparathyroidism.
T. Irie, T. Mawatari, S. Ikemura, Gen Matsui, T. Iguchi, H. Mitsuyasu   +5 more
semanticscholar   +1 more source

Magnetic Field‐Assisted Conductive Nerve Guidance Conduit Enabling Peripheral Nerve Regeneration with Wireless Electrical Stimulation

Advanced Functional Materials, EarlyView.
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu, Li‐Fang Zhu, Ming‐Wei Chang, Chao Li, Tingyu Wang, Rong Wang, Xinghao Yan, Baolin Wang   +7 more
wiley   +1 more source

BROWN TUMOR OF THE JAW: A RARE ENTITY

Romanian Journal of Oral Rehabilitation, 2018
Aim of the study The aim of this study is to present the development of brown tumors in the jaws as a consequence of secondary hyperparathyroidism (HPT).
Ciofu Mihai Liviu, Andrada Raluca Doscas, Andrei Nicolau, Christina Ungureanu, Daniel Timofte   +4 more
doaj  

Automatic Brain Tumor Segmentation using Cascaded Anisotropic Convolutional Neural Networks [PDF]

, 2017
A cascade of fully convolutional neural networks is proposed to segment multi-modal Magnetic Resonance (MR) images with brain tumor into background and three hierarchical regions: whole tumor, tumor core and enhancing tumor core. The cascade is designed to decompose the multi-class segmentation problem into a sequence of three binary segmentation ...
arxiv   +1 more source

HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia [PDF]

, 2020
Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured.
Bonetto, Andrea, Huot, Joshua R., Novinger, Leah J., Pin, Fabrizio   +3 more
core   +1 more source

3D In Vitro Glioma‐Neuron‐Astrocyte Biomimetic Composites Recapitulate Key Molecular Mechanisms Linked to Glioblastoma Multiforme Pathophysiology

Advanced Functional Materials, EarlyView.
Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier, Esra Türker, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Panthipa Suwannakot, Benedikt Gantert, Abhinav Singh, Vanessa Moessler, Annemarie Sodmann, Nicoletta Murenu, Joachim Schenk, Natascha Schaefer, Torsten Blunk, Aldo R. Boccaccini, Tessa C. Lühmann, Jörg Tessmar, Jeremy M. Crook, Eva Tomaskovic‐Crook, Paul D. Dalton, Gregor Lang, Robert Blum, Reiner Strick, Silvia Budday, Katrin G. Heinze, Carmen Villmann   +26 more
wiley   +1 more source