CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham +8 more
wiley +1 more source
Brown tumor of mandible: A conundrum towards the diagnosis. [PDF]
Shome S +3 more
europepmc +1 more source
Brown tumor due to primary hyperparathyroidism in a familial case: a case report. [PDF]
Diao Z, Zhang J, Zhao J, Sun W, Pu Z.
europepmc +1 more source
Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt +4 more
wiley +1 more source
Maxillary Brown Tumor Unveiling Primary Hyperparathyroidism: A Rare Diagnostic Challenge. [PDF]
Rehman A +4 more
europepmc +1 more source
Educational Case: Atypical presentation of primary hyperparathyroidism with brown tumor. [PDF]
Flotte A, Light J, Klause H, Conran RM.
europepmc +1 more source
Tooth mobility revealing a brown tumor associated with normocalcemic hyperparathyroidism: case report and literature review. [PDF]
Boukssim S, Damiri A, Chami B.
europepmc +1 more source
This review highlights the synthesis of chitosan nanoparticles from natural sources, the thorough characterization of them, and use of microscopic and spectroscopic methods. It emphasizes that it has some indispensable properties such as being non‐toxic, antimicrobial, and capable of controlled drug release.
Mariam Sohail Mansoor +6 more
wiley +1 more source
Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille +6 more
wiley +1 more source
Primary Hyperparathyroidism With Brown Tumor-A Case Mistaken as Non-Ossifying Fibroma Resolved by Biochemical and Radiological Correlation. [PDF]
Regmi D +4 more
europepmc +1 more source

