Results 191 to 200 of about 22,614 (265)

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1212-1224, June 2026.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Plasmonic Brownian Ratchets for Directed Transport of Analytes. [PDF]

Nano Lett
Palma do Carmo M, Mack D, Roth DJ, Zhao M, Devis AM, Rodríguez-Fortuño FJ, Maier SA, Huidobro PA, Rakovich A.   +8 more
europepmc   +1 more source

Cellular Heterogeneity in Drug Uptake Amplifies Pharmacodynamic Variability: A Stochastic PK‐PD Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Traditional pharmacokinetic‐pharmacodynamic models assume cellular homogeneity, yet clinical observations reveal substantial response variability even among patients with similar plasma exposure. We hypothesized that cellular heterogeneity in drug transporter expression, coupled with nonlinear dose–response relationships, can amplify ...
Nhung Hong‐Thi Duong, Tuan Ngoc Do, Tien Tran‐Nam Nguyen, Khanh Quoc Phan, Lap Thi Nguyen   +4 more
wiley   +1 more source

Enhanced diffusion over a periodic trap by hydrodynamic coupling to an elastic mode. [PDF]

Commun Phys
Lacherez J, Lavaud M, Amarouchene Y, Dean DS, Salez T.   +4 more
europepmc   +1 more source

Terrestrial Analogs to Titan for Geophysical Research

Reviews of Geophysics, Volume 64, Issue 2, June 2026.
Abstract Saturn's moon Titan exhibits remarkable parallels to the Earth in many geophysical and geological processes not found elsewhere in the solar system at the present day. These include a nitrogen atmosphere with a condensible gas—methane—replacing the Earth's water, leading to an active meteorology with rainfall and surface manifestations ...
Conor A. Nixon, Samuel Birch, Audrey Chatain, Charles Cockell, Kendra K. Farnsworth, Peter M. Higgins, Stéphane Le Mouélic, Rosaly M. C. Lopes, Michael J. Malaska, Mohit Melwani Daswani, Kelly E. Miller, Catherine D. Neish, Olaf G. Podlaha, Jani Radebaugh, Lauren R. Schurmeier, Ashley Schoenfeld, Krista M. Soderlund, Anezina Solomonidou, Christophe Sotin, Nicholas A. Teanby, Tetsuya Tokano, Steven D. Vance   +21 more
wiley   +1 more source

A discontinuity in motion perception during fixational drift. [PDF]

J Vis
D'Angelo JC, Tiruveedhula P, Weber RJ, Arathorn DW, Otero-Millan J, Roorda A.   +5 more
europepmc   +1 more source

Revealing the effects of anthropogenic structures on the spatial distribution of migratory wildebeest

Journal of Applied Ecology, Volume 63, Issue 6, June 2026.
In light of these findings, we recommend careful regulation and spatial planning of infrastructure development within ecosystems that consider the nuanced effects human‐made structures can have on the behaviour and habitat use of migratory animals. Abstract The increasing interaction between wildlife and humans, both within and outside protected areas,
Majaliwa M. Masolele, J. Grant C. Hopcraft, Christina L. Faust, Colin J. Torney   +3 more
wiley   +1 more source

Whisky-Inspired Active Matter. [PDF]

ACS Appl Mater Interfaces
Mohamed K, Henze K, Simmchen J.
europepmc   +1 more source

Confidence intervals for extinction risk: Validating population viability analysis with limited data

Methods in Ecology and Evolution, Volume 17, Issue 6, Page 1837-1850, June 2026.
Abstract The assessment of extinction risk remains a key component of IUCN and CITES evaluations. However, it has been argued that, under realistic data limitations, confidence intervals (CIs) for extinction probability often span the entire 0–1 range, rendering such assessments meaningless.
Hiroshi Hakoyama
wiley   +1 more source

Diffusion Properties of Small-Scale Fractional Transport Models. [PDF]

J Stat Phys
Cifani P, Flandoli F.
europepmc   +1 more source