Results 41 to 50 of about 237,678 (254)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Investigating students' web browsing performance based on their experience and mental model completeness level [PDF]
کتابداری و اطلاعرسانی, 2017 Purpose: This study aimed to investigate the role of mental models of undergraduate students at Shiraz University in the process of browsing the shopping websites according to their experience. Methodology: This was an applied research conducted through
Maryam Zolfaghari +2 more
doaj
Marine protected areas enhance coral reef functioning by promoting fish biodiversity
Conservation Letters, 2019 Preserving biodiversity and ecosystem function in the Anthropocene is one of humanity's greatest challenges. Ecosystem‐based management and area closures are considered an effective way to maintain ecological processes, especially in marine systems ...
Zachary M. Topor +3 more
doaj +1 more source
Rangifer, 2003 The effect of reindeer browsing on the regeneration of Betula pubescens subsp. czerepanovii and Salix phylicifolia was studied in a subarctic meadow in Finnish Lapland.
Michael den Herder, Pekka Niemelä
doaj +1 more source
Events and Controversies: Influences of a Shocking News Event on Information Seeking [PDF]
, 2014 It has been suggested that online search and retrieval contributes to the intellectual isolation of users within their preexisting ideologies, where people's prior views are strengthened and alternative viewpoints are infrequently encountered.
Bennett, Paul +2 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The Impact of Cattle Grazing on Shrub Biomass: A Review on Temperate Ecosystems
LandCattle grazing is particularly important to natural and semi-natural ecosystems, having often replaced grazing by smaller domestic ruminants such as goats and sheep.
Dimitrios Oikonomou +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Frontiers in Ecology and Evolution, 2021 In recent years, large predators have made a comeback across large parts of Europe. However, little is known about the impact that recolonizing predators may have on ecosystems with high degrees of anthropogenic influence.
Giorgia Ausilio +4 more
doaj +1 more source
The effect of WWW document structure on students' information retrieval [PDF]
, 1998 This experiment investigated the effect the structure of a WWW document has on the amount of information retained by a reader. Three structures common on the Internet were tested: one long page; a table of contents leading to individual sections; and ...
Brown, I
core +3 more sources