Results 51 to 60 of about 237,678 (254)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Tall willow thickets return to northern Yellowstone

open access: yesEcosphere, 2020
Northern Yellowstone National Park provides an example of passive restoration, as wetlands and riparian areas there lost most tall willows in the 20th century, due to intensive herbivory by elk (Cervus canadensis).
Luke E. Painter, Michael T. Tercek
doaj   +1 more source

Uncovering the different scales in deer–forest interactions

open access: yesEcology and Evolution, 2021
Deer are regarded to be a keystone species as they play a crucial role in the way an ecosystem functions. Most deer–forest interaction studies apply a single scale — process of analyzing ecological interactions by only taking into account one dependent ...
Juan Ignacio Ramirez
doaj   +1 more source

Implementasi Pembelajaran dengan Teknologi Video Based Learning

open access: yesInovasi Kurikulum, 2021
Pada era revolusi industry 4.0, banyak dari kita yang memanfaatkan internet sebagai pekerjaan sehari-hari. Contohnya seperti kita browsing untuk tujuan pembelajaran, berjualan online, membuka social media, registrasi akun dan lain lain.
Muhamad Haris Basyaev   +2 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Game damage to forest trees

open access: yesJournal of Forest Science, 2007
Humans should behave in such a way that they will not endanger the existence of other living entities. After all, human activities affected the tree species composition and wildlife living conditions.
V. Malík, P. Karnet
doaj   +1 more source

Físchlár on a PDA: handheld user interface design to a video indexing, browsing and playback system [PDF]

open access: yes, 2001
The Físchlár digital video system is a web-based system for recording, analysis, browsing and playback of TV programmes which currently has about 350 users.
Lee, Hyowon   +4 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Relationships between browsing damage and woody species dominance

open access: yesJournal of Forest Science, 2009
The paper analyzes data on browsing damage to food-attractive woody species, viz. Acer campestre, Acer pseudoplatanus, Acer platanoides, Fraxinus excelsior, Sorbus aucuparia and most often eudominant Fagus sylvatica.
P. Čermák   +3 more
doaj   +1 more source

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