Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej +20 more
wiley +2 more sources
This study was carried out for evaluation of the diagnostic performance of different serological assays; buffered acidified plate antigen test (BAPAT), rose bengal plate test (RBPT), immunochroma-tographic assay (ICA), rivanol test (RivT), indirect ELISA
S. Soliman +4 more
doaj +1 more source
Comparision of Brucella and Non-Brucella Epididymo-orchitis
To find parameters for differential diagnosis between Brucella epididymo-orchitis (BEO) and non-brucella epididymo-orchitis (NBEO) cases with comparison of BEO and NBEO in terms of inflammatory markers, full urinalysis (FU) for pyuria, and abscess formation (AF).Descriptive study.Agri State Hospital Urology and Infectious Disease Clinics, between ...
Nesibe, Korkmaz +2 more
openaire +3 more sources
Comparative proteomic analysis of outer membrane vesicles from Brucella suis, Brucella ovis, Brucella canis and Brucella neotomae [PDF]
Gram-negative bacteria release nanovesicles, called outer membrane vesicles (OMVs), from their outer membrane. Proteomics has been used to determine their composition. OMVs contain proteins able to elicit an immune response, so they have been proposed as a model to develop acellular vaccines. In this study, OMVs of Brucella suis, B. ovis, B. canis, and
María del Socorro Ruiz-Palma +9 more
openaire +2 more sources
BRUCELLOSIS SEROPOSITIVITY IN SHEEP SLAUGHTERED AT SMALL RUMINANT SLAUGHTERHOUSE IN BOGOR REGENCY
Brucellosis is among the important diseases in livestock because the disease infects multiple species of animals and causes economic loss. Brucellosis in sheep is generally caused by Brucella melitensis and/or Brucella ovis.
Widya Septiningtyas +2 more
doaj +1 more source
A Novel Arthropod Host of Brucellosis in the Arid Steppe Ecosystem
Brucellosis is a severe public health problem in the Inner Mongolia regions of China. The recent prevalence of brucellosis outbreaks may be attributed to an increase in the activity of ticks and other air-borne vectors. Dermacentor nuttalli (D. nuttalli)
Tianpeng Huang +6 more
doaj +1 more source
EVALUATION OF COOMBS TEST IN BRUCELLA DIAGNOSIS IN CATTLE AND SHEEP COMPARING WITH OTHER SEROLOGICAL TESTS. [PDF]
A total of 2406 cattle and 794 sheep blood samples were examined serologically for tube agglutination test (TAT). The reactor samples (33 cattle and 20 sheep) were subjected for Rose Bengal plate test (RBPT), buffered acidified plate test (BAPAT) and ...
M.M. ABDEL-HAFEEZ +3 more
doaj +1 more source
Approaches to increase recovery of bacterial and fungal abortion agents in domestic ruminants
Abortions in domestic ruminants cause significant economic losses to farmers. Determining the cause of an abortion is important for control efforts, but it can be challenging.
Annelize Jonker +2 more
doaj +1 more source
LDH as an adjuvant makes Brucella outer-membrane vesicles and outer-membrane vesicle-associated proteins highly protective in mice [PDF]
Objective(s): Existing Brucella vaccines are attenuated and can cause vaccine-associated brucellosis; and these safety concerns have affected their application.
Xiaoyu Deng +8 more
doaj +1 more source
Epidemiology of Brucellosis and Q Fever in Linked Human and Animal Populations in Northern Togo [PDF]
BACKGROUND: Although brucellosis (Brucella spp.) and Q Fever (Coxiella burnetii) are zoonoses of global importance, very little high quality data are available from West Africa. METHODS/PRINCIPAL FINDINGS: A serosurvey was conducted in Togo's main
Bassirou Bonfoh +15 more
core +3 more sources

