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The present study was undertaken to characterize the prevalence and molecular distinguishing of Brucella melitensis field and vaccine Rev1 strains isolated from milk among the sheep and goat population.
Elena AWWAD +9 more
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Towards aBrucellavaccine for humans [PDF]
There is currently no licensed vaccine for brucellosis in humans. Available animal vaccines may cause disease and are considered unsuitable for use in humans. However, the causative pathogen, Brucella, is among the most common causes of laboratory-acquired infections and is a Center for Disease Control category B select agent.
Stuart D, Perkins +2 more
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Ovine brucellosis is a global zoonotic disease of sheep caused by Brucella melitensis, which inflicts a significant burden on human and animal health. Brucella suis strain S2 (B.
Si Chen +17 more
doaj +1 more source
We have estimated the effects of the Brucella abortus 19 ВА inactivated vaccine, thermo extracts of Brucella abortus I-206 in the L- and S-forms and corpuscular antigen of Brucella abortus I-206 in L-form on the population and subpopulation structure of ...
S. A. Vityazeva +7 more
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Brucella is a Gram-negative, facultative intracellular bacterium that causes zoonotic brucellosis in humans and various animals. Out of ten classified Brucella species, B. melitensis, B. abortus, B. suis, and B. canis are pathogenic to humans.
Yongqun eHe
doaj +1 more source
Improved influenza viral vector based Brucella abortus vaccine induces robust B and T-cell responses and protection against Brucella melitensis infection in pregnant sheep and goats. [PDF]
We previously developed a potent candidate vaccine against bovine brucellosis caused by Brucella abortus using the influenza viral vector expressing Brucella Omp16 and L7/L12 proteins (Flu-BA).
Aigerim Mailybayeva +7 more
doaj +1 more source
Rev1 wbdR tagged vaccines against Brucella ovis [PDF]
AbstractSheep brucellosis is a worldwide extended disease caused by B. melitensis and B. ovis, two species respectively carrying smooth or rough lipopolysaccharide. Vaccine B. melitensis Rev1 is used against B. melitensis and B. ovis but induces an anti-smooth-lipopolysaccharide response interfering with B. melitensis serodiagnosis, which precludes its
Beatriz Aragón-Aranda +8 more
openaire +7 more sources
Seroprevalence of Q fever in sheep and goats from the Marmara region, Turkey
The aim of this study was to investigate Q fever seroprevalence in sheep and goats in the Marmara region. Q fever is a zoonotic disease caused by Coxiella burnetii. In ruminants, the disease causes reproductive disorders, premature births and stillbirths.
Karagul Mustafa Sencer +2 more
doaj +1 more source
Multivalent Fusion DNA Vaccine againstBrucella abortus [PDF]
As an alternative brucellosis prevention method, we evaluated the immunogenicity induced by new multivalent DNA vaccines in BALB/c mice. We constructed the vaccines by fusion of BAB1_0273 and/or BAB1_0278 open reading frames (ORFs) from genomic island 3 (GI-3) and theBrucella abortus2308sodCgene with a link based on prolines and alanines (pV273-sod ...
Leonardo Gómez +7 more
openaire +2 more sources
Identification of potential antigenic peptides of Brucella through proteome and peptidome
Background Brucellosis, caused by Brucella spp., is a major zoonotic public health threat. Although several Brucella vaccines have been demonstrated for use in animals, Brucella spp.
Meijuan Pei +10 more
doaj +1 more source

