Results 41 to 50 of about 28,396 (180)
An investigation of novel DNA based vaccines for protection against Brucellosis [PDF]
This thesis describes design, construction and evaluation in a BALB/c mouse model, for five novel Brucella specific DNA vaccines. Brucellosis is worldwide zoonosis of economic significance that poses a significant threat to both animal and human health ...
Commander, Nicola Jane
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TTK Overexpression: A Negative Prognostic Biomarker in Anaplastic Thyroid Carcinoma
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Background Given threonine and tyrosine kinase (TTK)'s oncogenic role in various cancers and its understudied status in thyroid cancer, this study investigates TTK expression in thyroid lesions to assess its diagnostic and therapeutic potential. Methods We analyzed differential TTK expression levels using public datasets (n = 143) and clinical
Yan Guo +7 more
wiley +1 more source
Difficulties of differential diagnosis of lymphadenopathy in acute brucellosis (clinical cases)
, 2023 Brucellosis is a zoonotic disease caused by bacteria of the genus Brucella, characterized by prolonged fever with damage to the musculoskeletal system, nervous, reproductive, cardiovascular and other systems, prone to chronic course.
Nikita A. Tereshkin +3 more
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Hepatic Sarcoidosis Unmasked by Chronic Pruritus and Esophageal Varices: A Case Report
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Sarcoidosis is a granulomatous disease that affects multiple organs, commonly the liver, with manifestations from asymptomatic disease to cirrhosis and liver failure. A 43‐year‐old male presented with generalized pruritus. Liver biopsy demonstrated findings consistent with sarcoidosis, and treatment was initiated. We emphasize timely follow‐up
Ming Zheng +2 more
wiley +1 more source
Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1170-1181, June 2026.ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu +9 more
wiley +1 more source
The development of immunoassays for the detection of bovine brucellosis and aflatoxin B1 [PDF]
, 2004 The research discussed in this thesis focuses on the development and characterisation of immunoassays for the detection of aflatoxin Bi (AFBi), a toxic fungal metabolite, and for the diagnosis of bovine brucellosis, a highly contagious disease of cattle ...
Dunne, Lynsey
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Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang +3 more
wiley +1 more source
Brucellosis: an Overview [PDF]
Emerging Infectious Diseases, 1997 Brucellosis remains a major zoonosis worldwide. Although many countries have eradicated Brucella abortus from cattle, in some areas Brucella melitensis has emerged as a cause of infection in this species as well as in sheep and goats. Despite vaccination campaigns with the Rev 1 strain, B.
openaire +3 more sources
Public Health Challenges, Volume 5, Issue 2, June 2026.This study highlights that most consumers recognize that meat can transmit zoonotic diseases. However, substantial gaps persist in specific knowledge and in the consistent adoption of safe handling practices. By combining community education, improved market hygiene and One Health initiatives, policy‐makers can substantially reduce exposure to zoonotic
Madi Savadogo +6 more
wiley +1 more source
GeoHealth, Volume 10, Issue 6, June 2026.Abstract Melioidosis is a potentially fatal tropical disease caused by the environmentally mediated bacterium, Burkholderia pseudomallei. In Vietnam, melioidosis is not nationally reportable and little is known regarding its epidemiology and distribution in the northernmost mountainous provinces.
Morgan C. Metrailer +14 more
wiley +1 more source