Results 21 to 30 of about 9,814 (188)

Renal Dopamine Oxidation and Inflammation in High Salt Fed Rats

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Oxidative stress and high salt intake could be independent or intertwined risk factors in the origin of hypertension. Kidneys are the major organ to regulate sodium homeostasis and blood pressure and the renal dopamine system plays a pivotal ...
Anees A. Banday, Mustafa F. Lokhandwala
doaj   +1 more source

An in situ self‐assembled peptide derivative for inhibition of glutathione synthesis and selective enhancement of tumor radiotherapy

iRADIOLOGY, 2023
Background Inhibition of glutathione (GSH) synthesis in cancer cells considerably improves the efficacy of reactive oxygen species (ROS)‐related tumor therapy.
Xinyan Gong, Benhang Cui, Paiyun Li, Jie Gao, Yang Gao, Xiaoyao Cai, Hang Wang, Wenxue Zhang, Cuihong Yang   +8 more
doaj   +1 more source

Brain Storm Optimization for Multiple Sequence Alignment problem [PDF]

Assiut University Journal of Multidisciplinary Scientific Research, 2022
Brain Storm Optimization (BSO) is one of the most effective swarm intelligence methods for finding optimality in optimization problems by simulating the human brainstorming process.
doaj   +1 more source

Effects of black seed oil combined with olive oil or honey on antioxidant activities, phenolic content, and identification and quantification of thymoquinone, a key bioactive compound

Journal of Agriculture and Food Research, 2023
The plant Nigella sativa (NS) has a rich history in folk medicine, being utilized for various illnesses and as tonic drugs. Furthermore, thymoquinone (TQ), a major compound found in the seeds of NS, may exhibit antioxidant activity.
Sakan Warinhomhoun, Sineenart Sanpinit, Piriya Chonsut, Ngamrayu Ngamdokmai, Aktsar Roskiana Ahmad, Palika Wetchakul   +5 more
doaj   +1 more source

BSO-CNN: A BSO Pressure Optimized CNN Model for Water Distribution Networks

Tehnički glasnik
Urban water distribution networks must use pressure management to reduce water leakage by modifying storage tank pressure levels in response to variations in water demand. Since each demand node usually restricts the maximum pressure that may be applied, addressing pressure issues at individual nodes is also crucial.
Waghmare Shwetambari Pandurang, Renu Praveen Pathak, Imtiyaz Ahmad Wani   +2 more
openaire   +3 more sources

Effect of Taro Corm Mucilage and Black Seed Oil as Edible Coatings on the Shelf-Life and Quality of Fresh Guava

Agronomy, 2023
This study aimed to assess the influence of taro mucilage (TM) and black seed oil (BSO) as an edible coating to extend guava fruits’ shelf-life and quality attributes. Four different edible coatings were applied, namely, T1 (1% TM + 0.75% glycerol + 0.5%
Sumaiya Sultana Shanta, Tanvir Ahmed, Md Fahad Jubayer, Minaxi Sharma, Kandi Sridhar, Md Mozammel Hoque, Md Rahmatuzzaman Rana, Baskaran Stephen Inbaraj   +7 more
doaj   +1 more source

Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer

Advanced Science, EarlyView.
The schematic diagram depicts a compartmentalized anti‐ferroptotic defense mechanism mediated by GSTA4. GSTA4 is upregulated and localizes to the cytoplasm in ENZR cells, where it detoxifies 4‐HNE via a non‐canonical GSH‐dependent pathway. Under oxidative stress, GSTA4 translocates to mitochondria, interacts with PGAM5, and blocks Drp1 Ser637 ...
Yong Luo, Wei Zhuang, Zean Li, Yiming Lai, Yongyi Ou, Dongquan Li, Shanhe Huang, Tianlong Luo, Jintao Hu, Bingliang Chen, Jianhan Fu, Tao Zhuo, Hankun Jiang, Yin Lu, Hai Huang, Kewei Xu, Shengmeng Peng, Qing Yuan   +17 more
wiley   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

Suppressive effects of black seed oil on ovalbumin induced acute lung remodelling in E3 rats

Swiss Medical Weekly, 2010
OBJECTIVE: Black seed oil (BSO) is widely used as a traditional medicine for asthma and other inflammatory diseases. The aim of this study is to evaluate the effects of BSO on ovalbumin (OVA) induced acute lung remodelling in E3 inbred rats.
M Shahzad, X Yang, Q Sun, F Zhang, Y Han, S Lu, Asim Raza   +6 more
doaj   +1 more source

A Hybrid BSO-ACO for Dynamic Vehicle Routing Problem on Real-World Road Networks

IEEE Access, 2022
The Dynamic Vehicle Routing Problem With Time Windows (DVRPTW) is an NP-hard problem, which has attracted a lot of attention in the past decades due to its many practical applications in logistics.
Mingde Liu, Qi Song, Qi Zhao, Ling Li, Zhiming Yang, Yingbin Zhang   +5 more
doaj   +1 more source