Indirect treatment comparison of brexucabtagene autoleucel (ZUMA-2) versus standard of care (SCHOLAR-2) in relapsed/refractory mantle cell lymphoma [PDF]
The SCHOLAR-2 retrospective study highlighted poor overall survival (OS) with standard of care (SOC) regimens among patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) who failed a covalent Bruton tyrosine kinase inhibitor (BTKi).
Chen J. M. H. +24 more
core +1 more source
BTKi +humanized anti-CD20 for advanced follicular lymphoma: ready for an ALTERNATIVE?
Not available.
Irene Dogliotti, Massimo Federico
openaire +2 more sources
Background: The advent of Bruton's tyrosine kinase inhibitors (BTKi) has revolutionized the treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). BTKi are administered continuously until progression or unacceptable toxicity.
M. Bullo +7 more
doaj
A 3-week pause versus continued Bruton tyrosine kinase inhibitor use during COVID-19 vaccination in individuals with chronic lymphocytic leukaemia (IMPROVE trial): a randomised, open-label, superiority trial [PDF]
SummaryBackground Chronic lymphocytic leukaemia is the commonest leukaemia and is associated with profoundimmunosuppression. Bruton tyrosine kinase inhibitors (BTKi) have revolutionised chronic lymphocytic leukaemiamanagement; however, therapy impairs ...
Hutchinson, Claire, Parry, Helen M.
core +8 more sources
Off-axis impact of unidirectional composites with cracks: Dynamic stress intensification [PDF]
The dynamic response of unidirectional composites under off axis (angle loading) impact is analyzed by assuming that the composite contains an initial flaw in the matrix material.
Chen, E. P., Sih, G. C.
core +1 more source
Correlation between Real-World Progression-Free Survival (rwPFS) and Overall Survival (OS) in Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Who Relapsed or Are Refractory, Intolerant, Resistant to Treatment with a Bruton's Tyrosine Kinase Inhibitor (BTKi) [PDF]
Kevin Lin +15 more
openalex +1 more source
Our findings provide a snapshot of the current therapeutic landscape in WM after cBTKi failure. Importantly, although none of the baseline disease characteristics influenced response to cBTK‐S, the sample size is too small to make any powered evaluation. On this basis, there is an urgent need for approval in this setting.
Anna Maria Frustaci +29 more
openaire +8 more sources
Rituximab in a risk-adapted treatment strategy gives excellent therapeutic results in nodular lymphocyte-predominant Hodgkin lymphoma [PDF]
Cerchione, Claudio +11 more
core +1 more source

