Results 151 to 160 of about 573,339 (226)
Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang+9 more
wiley +1 more source
Investigation of incipient cavitation in various liquids based on PIV quantification and numerical simulations. [PDF]
Chen J+8 more
europepmc +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Quantitative Characterization of Bubble Defects in Ultra-Low Expansion Quartz Glass via Ultrasonic Interaction. [PDF]
Zhou L+5 more
europepmc +1 more source
Silicon Nanowire Mats Enable Advanced Bioelectrical Recordings in Primary DRG Cell Cultures
SiNW mat‐based MEA (NW_MEA) enables continuous intracellular recordings from neurons in primary rat DRG cell cultures, identifying C‐fiber nociceptors. Supported by an astrocyte feeder layer, SiNW mat promotes DRG neuron and glial cell growth, preserving in vivo‐like cell characteristics and allowing drug‐modulated activity monitoring.
Ivano Lucarini+12 more
wiley +1 more source
Photosynthetic oxygen bubble stream sounds from aquatic macrophytes, and their consequences for acoustic biodiversity inventories and acoustic communication in shallow freshwater settings. [PDF]
Campbell K, Cerezke-Riemer Y, Acorn JH.
europepmc +1 more source
Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre+5 more
wiley +1 more source
Mass transfer of acoustic cavitation bubbles in multi-bubble environment. [PDF]
Hattori KD, Yamamoto T.
europepmc +1 more source
Engineered exosome‐based heavy atom‐free nanosensitizers are developed for safe and targeted sono‐photodynamic therapy of solid tumors. The IR820‐TPE‐loaded, biotin‐conjugated exosomes (IR820‐TPE@B‐Exo) demonstrate significant promise for NIR fluorescence imaging‐guided sono‐photodynamic cancer therapy.
Van‐Nghia Nguyen+16 more
wiley +1 more source