Biopharmaceutical Study of Triamcinolone Acetonide Semisolid Formulations for Sublingual and Buccal Administration [PDF]
Pharmaceutics, 2021 The mouth can be affected by important inflammatory processes resulting from localized or systemic diseases such as diabetes, AIDS and leukemia, among others, and are manifested in various types of buccal sores typically presenting pain.
Marta Márquez Valls +7 more
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A novel dosage form for buccal administration of bupropion [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2015 Bupropion is an antidepressant used in the treatment of smoking. The purpose of this study was to prepare controlled-release hydrogel films for buccal administration of bupropion and investigate its physicochemical and cytotoxic properties.
Nilsa Maria Galvão Almeida +5 more
doaj +6 more sources
Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration [PDF]
Frontiers in Pharmacology, 2019 The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required ...
Susan Hua, Susan Hua
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Buccal administration of mucoadhesive blend films saturated with propranolol loaded nanoparticles [PDF]
Asian Journal of Pharmaceutical Sciences, 2018 The aims of this study were to prepare and characterize hydroxypropyl methylcellulose (HPMC)/polycarbophil (PC) mucoadhesive blend films saturated with propranolol hydrochloride (PNL)-loaded nanoparticles to improve permeability of drugs that undergo ...
Pakorn Kraisit +3 more
doaj +5 more sources
Preformulation Studies of Furosemide-Loaded Electrospun Nanofibrous Systems for Buccal Administration. [PDF]
Polymers (Basel), 2017 Furosemide loaded electrospun fibers were prepared for buccal administration, with the aim of improving the oral bioavailability of the poorly soluble and permeable crystalline drug, which can be achieved by the increased solubility and by the circumvention of the intensive first pass metabolism.
Kovács A +3 more
europepmc +7 more sources
Midazolam pharmacokinetics following intravenous and buccal administration [PDF]
British Journal of Clinical Pharmacology, 1998 Aims Midazolam has good anxiolytic qualities and is a well established premedication agent before anaesthesia or short surgical procedures. The objective of the present study was to determine pharmacokinetic data from individual plasma concentration profiles obtained following intravenous and buccal administration of midazolam.
Rolf Schwagmeier +2 more
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Mucoadhesive Tablets for Buccal Administration Containing Sodium Nimesulide [PDF]
Drug Delivery, 2004 The possibility of improving the flux of nimesulide across the buccal mucosa using the drug in the form of a sodium salt was investigated in our study. The salt form may increase to flux across buccal membrane, starting from a suspension; its lower permeation coefficient is compensated by a higher concentration gradient.
P. Maffei +6 more
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Incorrect administration of buccal glyceryl trinitrate [PDF]
Heart, 2002 A 66 year old man with documented coronary artery disease was brought by ambulance to the emergency department with severe anginal chest pain and pulmonary oedema. Two 2 mg buccal glyceryl trinitrate …
A. H. D. Watson, Lisa A. Michaels
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Preparation, optimization, and evaluation of midazolam nanosuspension: enhanced bioavailability for buccal administration. [PDF]
Prog Biomater, 2021 Soroushnia A +3 more
europepmc +3 more sources
MUCOADHESIVE POLYMERIC FILMS OF ACYCLOVIR PRONIOSOMES FOR BUCCAL ADMINISTRATION
International Journal of Applied Pharmaceutics, 2021 Objective: The aim of the present work was to formulate and evaluate proniosomes of the poorly soluble drug, acyclovir incorporated in mucoadhesive polymeric films for improved buccal mucosal permeability of the drug while achieving prolonged release. Methods: Acyclovir was formulated as proniosomes using Span 60 and cholesterol.
DEEKSHA U. SUVARNA +3 more
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