Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration [PDF]
The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required ...
Susan Hua, Susan Hua
doaj +4 more sources
A novel dosage form for buccal administration of bupropion [PDF]
Bupropion is an antidepressant used in the treatment of smoking. The purpose of this study was to prepare controlled-release hydrogel films for buccal administration of bupropion and investigate its physicochemical and cytotoxic properties.
Nilsa Maria Galvão Almeida +5 more
doaj +5 more sources
Buccal administration of mucoadhesive blend films saturated with propranolol loaded nanoparticles [PDF]
The aims of this study were to prepare and characterize hydroxypropyl methylcellulose (HPMC)/polycarbophil (PC) mucoadhesive blend films saturated with propranolol hydrochloride (PNL)-loaded nanoparticles to improve permeability of drugs that undergo ...
Pakorn Kraisit +3 more
doaj +3 more sources
Biopharmaceutical Study of Triamcinolone Acetonide Semisolid Formulations for Sublingual and Buccal Administration [PDF]
The mouth can be affected by important inflammatory processes resulting from localized or systemic diseases such as diabetes, AIDS and leukemia, among others, and are manifested in various types of buccal sores typically presenting pain.
Marta Márquez Valls +7 more
doaj +2 more sources
Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats. [PDF]
The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in ...
Doodnaught GM +6 more
europepmc +5 more sources
Absorption of clonazepam after intranasal and buccal administration. [PDF]
Serum concentrations of clonazepam after intranasal, buccal and intravenous administration were compared in a cross‐over study in seven healthy male volunteers. Each subject received a 1.0 mg dose of clonazepam intranasally and buccally and 0.5 mg intravenously.
M W, Schols-Hendriks +5 more
openaire +4 more sources
Marvin Omar Delgado-GuayDivision of Geriatrics and Palliative Medicine, The University of Texas, Medical School at Houston, Houston, TX, USAAbstract: More than half of patients receiving prescription medicine for cancer pain have been reported to ...
Marvin Omar Delgado-Guay
doaj +4 more sources
Comparative bioavailability study following a single dose intravenous and buccal administration of remdesivir in rabbits. [PDF]
Szente L +7 more
europepmc +3 more sources
PHARMACOKINETICS OF MORPHINE FOLLOWING ADMINISTRATION BY THE BUCCAL ROUTE
The pharmacokinetics of morphine administered via the buccal route as a controlled release formulation were assessed after the administration of three different doses and found to be linear in the dose range 10-30 mg. The plasma concentrations of morphine-3-glucuronide and morphine-6-glucuronide demonstrated considerable inter-subject variation and ...
A R, Manara +3 more
openaire +3 more sources

