Results 131 to 140 of about 49,757 (329)

Variation in Neurodegeneration‐Linked Brain Regions in Young Adult APOE E4 Carriers With Spina Bifida

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Possible pleiotropic effects of apolipoprotein E4 (APOE E4) in individuals with congenital brain malformations are relatively unknown. Our goal was to determine if neurodegeneration‐linked brain region volumes differ significantly between E4 carriers and noncarriers in young adults with spina bifida (SB). Methods Eleven individuals ( 
Joan M. Jasien, Jacques A. Stout, Mohamad A. Mikati, Robert J. Anderson, Brittany G. Nave, Herbert E. Fuchs, Brian Smith, Alexandra Badea, Jeffrey N. Browndyke   +8 more
wiley   +1 more source

Self-Reported Effectiveness and Safety of Trokie® Lozenges: A Standardized Formulation for the Buccal Delivery of Cannabis Extracts

Frontiers in Neuroscience, 2018
Therapeutic use of cannabinoids, the main active ingredients of Cannabissativa L., is often hindered by their limited bioavailability and undesirable psychoactivity. We conducted an observational study in December 2016 and another one in February 2018 to
Kenton Crowley, Sieta T. de Vries, Guillermo Moreno-Sanz, Guillermo Moreno-Sanz   +3 more
doaj   +1 more source

85: Buccal versus vaginal misoprostol administration for cervical ripening [PDF]

, 2007
Zoi Russell, Timothy J. O’Leary, Kimberly Destefano, Aaron J. Deutsch, S. J. Carlan   +4 more
openalex   +1 more source

Progress in Pharmacogenomics Implementation in the United States: Barrier Erosion and Remaining Challenges

Clinical Pharmacology &Therapeutics, EarlyView.
Barriers to incorporating pharmacogenetics into routine clinical practice in the United States are well documented. Initial surveys by the Clinical Pharmacogenetics Implementation Consortium (CPIC) in 2009 and 2010 identified barriers across four key domains that have hindered the widespread adoption of clinical pharmacogenetic testing.
D. Max Smith, Michael P. Douglas, Christina L. Aquilante, Patricia A. Deverka, Beth Devine, Henry M. Dunnenberger, Philip E. Empey, Daniel L. Hertz, Andrew A. Monte, Ann M. Moyer, Jai N. Patel, Victoria M. Pratt, Loren Saulsberry, Stuart A. Scott, Deepak Voora, Erica L. Woodahl, Michelle Whirl‐Carrillo, Akinyemi Oni‐Orisan, on behalf of the Pharmacogenomics Global Research Network (PGRN) Publications Committee   +18 more
wiley   +1 more source

The aging male: investigation, treatment and monitoring of late-onset hypogonadism in males [PDF]

, 2006
Androgen deficiency in the aging male has become a topic of increasing interest and debate throughout the world. The demographics clearly demonstrate the increasing percentage of the population that is in the older age groups.
Behre, Hermann M., Gooren, L. J., Kaufman, J. M., Legros, J. J., Lunenfeld, Bruno, Morley, John E., Nieschlag, Eberhard, Schulman, C., Swerdloff, Ronald, Wang, C., Weidner, W., Wu, F. C. W.   +11 more
core  

Syringic acid may attenuate the oral mucosal carcinogenesis via improving cell surface glycoconjugation and modifying cytokeratin expression

Toxicology Reports, 2018
Syringic acid (SRA) is an excellent anti-oxidant and anti-cancer property in various in vitro and in vivo studies. In the present study was modifying effect of SRA on 7,12-dimethylbenz(a)anthracene (DMBA) induced cell surface glycoconjugates (GCs ...
Velu Periyannan, Vinothkumar Veerasamy
doaj  

Medications used for seizure‐emergency management in the UK community: A clinical practice research datalink retrospective database study

Epilepsia Open, EarlyView.
Abstract Objective Assess the prevalence, characteristics, and healthcare resource utilization (HCRU) of patients prescribed certain benzodiazepines for seizure‐emergency management in the United Kingdom. Methods Retrospective cohort study using Clinical Practice Research Datalink (CPRD‐Aurum) and Hospital Episode Statistics (HES) data that included ...
Yuanjun Ma, Chao Lu, Peggy Hastie, Ana Paula Bartmann, Cédric Laloyaux, Simon Borghs   +5 more
wiley   +1 more source

Gingival Abscess Removal Using a Soft-Tissue Laser [PDF]

, 2011
Gingival abscess, also known as parulis, is defined as a localized, acute inflammatory lesion that may arise from a number of sources, including microbial plaque infection, trauma, and foreign body impaction. It often presents as a smooth, fluctuant, red-
Andreana, Sebastiano, Monaco, Jr., Edward A., Prasad, Soni   +2 more
core   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Exploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li, Haonan Xing, Abid Naeem, Kaiyue Zhang, Aiping Zheng, Yuanyu Huang, Mei Lu   +6 more
wiley   +1 more source

Functional Characteristics of Bioactive Millet Peptides: A Comprehensive Review

Future Postharvest and Food, EarlyView.
The graphical abstract of this paper highlights the functional characteristics of bioactive peptides derived from millets. It is a promising ingredient and can be used in various applications in food, pharmaceuticals, and healthcare industries and possess biological functions.
Kouser Jan, Aamir Hussain Dar, Kshirod Kumar Dash, Shivangi Srivastava, Vinay Kumar Pandey, Parmjit S. Panesar, Wani Suhana Ayoub, Entesar Hanan, Iqra Bashir, Anurag Singh, Shafat Ahmad Khan   +10 more
wiley   +1 more source