A novel dosage form for buccal administration of bupropion [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2015 Bupropion is an antidepressant used in the treatment of smoking. The purpose of this study was to prepare controlled-release hydrogel films for buccal administration of bupropion and investigate its physicochemical and cytotoxic properties.
Nilsa Maria Galvão Almeida +5 more
doaj +7 more sources
Preparation, optimization, and evaluation of midazolam nanosuspension: enhanced bioavailability for buccal administration. [PDF]
Prog Biomater, 2021 Soroushnia A +3 more
europepmc +4 more sources
Ondansetron buccal administration for paediatric use: A comparison between films and wafers [PDF]
International Journal of Pharmaceutics, 2020 The objective of this study was the development of different solid formulations, such as wafers and films, for buccal administration of ondansetron, a selective and potent antagonist of 5-hydroxytryptamine 3 receptors used in children for the treatment of nausea and vomiting.
Barbara Giordani +7 more
semanticscholar +5 more sources
Preformulation Studies of Furosemide-Loaded Electrospun Nanofibrous Systems for Buccal Administration. [PDF]
Polymers (Basel), 2017 Furosemide loaded electrospun fibers were prepared for buccal administration, with the aim of improving the oral bioavailability of the poorly soluble and permeable crystalline drug, which can be achieved by the increased solubility and by the ...
Kovács A +3 more
europepmc +8 more sources
Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration. [PDF]
Int J Pharm X, 2021 Kottke D +4 more
europepmc +4 more sources
Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats. [PDF]
PLoS One, 2017 The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in ...
Doodnaught GM +6 more
europepmc +6 more sources
Preparation and Characterization of Polymeric Mucoadhesive Film for Buccal Administration [PDF]
British Journal of Pharmaceutical Research, 2014 Objectives: Buccal films consist mainly of polymer that has a good mucoadhesive profile and plasticizer. A lot of polymers and plasticizers can be used to configure the mucoadhesive films as hydroxyethyl cellulose and glycerin respectively.
Ramy Gales
semanticscholar +4 more sources
Efficacy and safety of fentanyl buccal for cancer pain management by administration through a soluble film: an update [PDF]
Cancer Management and Research, 2010 Marvin Omar Delgado-GuayDivision of Geriatrics and Palliative Medicine, The University of Texas, Medical School at Houston, Houston, TX, USAAbstract: More than half of patients receiving prescription medicine for cancer pain have been reported to ...
Marvin Omar Delgado-Guay
doaj +7 more sources
Drug-Loaded Lipid-Core Micelles in Mucoadhesive Films as a Novel Dosage Form for Buccal Administration of Poorly Water-Soluble and Biological Drugs. [PDF]
Pharmaceutics, 2020 The aim of the study was to develop a novel buccal dosage form to transport rhodamine 123 and human insulin as models for poorly water-soluble and biological drugs, using lipid-core micelles (LCMs)-loaded mucoadhesive films.
Chou WH +4 more
europepmc +4 more sources
Absolute Bioavailability of Microdosed Midazolam After Buccal Administration Is Dependent on Buccal Exposure Time. [PDF]
The Journal of Clinical Pharmacology, 2020 Midazolam is an established probe drug to assess cytochrome P450 3A activity (phenotyping). Microdosed midazolam is increasingly used for this purpose; a buccal formulation might be of advantage, but buccal absorption might occur.
J. Grass +5 more
semanticscholar +4 more sources