Pharmacokinetics of testosterone after percutaneous gel or buccal administration [PDF]
Fertility and Sterility, 2001 To determine the pharmacokinetics of testosterone following its administration using transdermal gel or buccal lozenges.Pilot study.University-based hospital.Ten bilaterally oophorectomized women.Daily micronized testosterone gel (1 mg) and testosterone propionate lozenge (1 mg).Total testosterone, androstenedione, dihydrotestosterone, 3alpha ...
Cristin C. Slater +5 more
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Significant hypotension following buccal midazolam administration [PDF]
BMJ Case Reports, 2010 Buccal midazolam is a rescue medication to reduce the duration of or stop an epileptic seizure, and is used to prevent status epilepticus. It is available in various forms, including a buccal preparation with a strength of 10 mg/1 ml. Midazolam is a licensed medication, but the buccal formulation is currently used off-licence.
M. Kensche +2 more
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PHARMACOKINETICS OF MORPHINE FOLLOWING ADMINISTRATION BY THE BUCCAL ROUTE
British Journal of Anaesthesia, 1989 The pharmacokinetics of morphine administered via the buccal route as a controlled release formulation were assessed after the administration of three different doses and found to be linear in the dose range 10-30 mg. The plasma concentrations of morphine-3-glucuronide and morphine-6-glucuronide demonstrated considerable inter-subject variation and ...
Alexander R. Manara +3 more
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Cancer Management and Research, 2010 Marvin Omar Delgado-GuayDivision of Geriatrics and Palliative Medicine, The University of Texas, Medical School at Houston, Houston, TX, USAAbstract: More than half of patients receiving prescription medicine for cancer pain have been reported to ...
Marvin Omar Delgado-Guay
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Ondansetron buccal administration for paediatric use: A comparison between films and wafers [PDF]
International Journal of Pharmaceutics, 2020 The objective of this study was the development of different solid formulations, such as wafers and films, for buccal administration of ondansetron, a selective and potent antagonist of 5-hydroxytryptamine 3 receptors used in children for the treatment of nausea and vomiting.
Barbara Giordani +7 more
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Serum morphine concentrations after buccal and intramuscular morphine administration. [PDF]
British Journal of Clinical Pharmacology, 1987 1. This study compared serum concentrations of morphine after administration of a buccal tablet (25mg) with those after intramuscular injection (10mg). 2. Buccal morphine was administered to eleven healthy volunteers and intramuscular morphine was given to five preoperative surgical patients.
A. P. Fisher, C. FUNG, Michael G. Hanna
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Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration. [PDF]
Int J Pharm X, 2021 Kottke D +4 more
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Pharmacokinetics of butorphanol in cats after intramuscular and buccal transmucosal administration [PDF]
American Journal of Veterinary Research, 2008 Abstract Objective—To determine the pharmacokinetics of butorphanol in cats following IM and buccal transmucosal (BTM) administration, to determine the relative bioavailability of butorphanol following BTM administration, and to extrapolate a plasma concentration associated with antinociception on the basis of existing data from pharmacologic studies ...
Sean M. Wells +2 more
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Buccal Administration of a Zika Virus Vaccine Utilizing 3D-Printed Oral Dissolving Films in a Mouse Model. [PDF]
Vaccines (Basel)Shah S +10 more
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5-methyl-pyrrolidinone chitosan films as carriers for buccal administration of proteins [PDF]
AAPS PharmSciTech, 2006 The purpose of this research was to investigate 5-methyl-pyrrolidinone chitosan (MPC) films as carriers for buccal delivery of protein drugs. Placebo and protein-loaded MPC films were prepared by casting and were then cross-linked with tripolyphosphate at different pH conditions.
C. Colonna +7 more
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