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Bioavailability of Flurbiprofen Following Buccal Administration
Pharmaceutical Research, 1991The buccal absorption of flurbiprofen was evaluated in nine normal volunteers. Twenty milliliters of 2.5 mg/ml flurbiprofen solution (pH 8.03) was administered as a 1-min mouthwash or a 5-min mouthwash or swallowed. Serum was harvested from blood samples taken at specified times over a 12-hr period.
D J, Stalker, S R, Pollock
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Buccal versus intravaginal misoprostol administration for cervical ripening
American Journal of Obstetrics and Gynecology, 2002The purpose of this study was to compare the efficacy of misoprostol that is administered in the buccal pouch with the intravaginal route of administration.One hundred fifty-seven pregnant women with a singleton live gestation, Bishop score of
S J, Carlan +2 more
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Development of an Insulin Nano-delivery System through Buccal Administration
Current Drug Delivery, 2022Aim: The aim of the study was to develop a new nano-delivery system for buccal administration of insulin. Background: Biodegradable polymeric nanoparticles (PNPs) had undergone countless breakthroughs in drug delivery systems. The main objective of PNPs application in delivering and carrying different promising drugs is to make sure that the drugs ...
Ayat Bozeya +2 more
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Sublingual and buccal drug administration in medical emergencies
Medicina ClĂnica (English Edition)Drug administration is crucial to achieve effective therapeutic drug outcomes. In medical emergencies, it is particularly convenient to use drugs that could be administered as an alternative to traditional routes (as oral or intravenous routes), that are not always suitable in these situations. Thus, sublingual and buccal routes offer an alternative to
Joan Ramon, Roma +2 more
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Buccal administration of dexmedetomidine as a preanesthetic in children
Journal of Anesthesia, 2010The objective of this study was to evaluate the efficacy and safety of buccal dexmedetomidine as a preanesthetic in children, to compare it with diazepam, and to investigate the optimal dosage for buccal dexmedetomidine administration by measuring its serum concentration.We performed a prospective study with 40 children who were assigned to two groups.
Yoshio, Sakurai +5 more
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Systemic uptake of buprenorphine after buccal administration in cats
Veterinary Anaesthesia and Analgesia, 2002Administration of drugs to cats can be challenging and simple but effective techniques would be attractive to the owners. The purpose of this study was to compare the pharmacokinetics of buprenorphine (B) after buccal administration, and compare these to data previously collected from the same colony of cats after IV and IM injection.
S A, Robertson +3 more
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