Results 21 to 30 of about 27,341 (167)
Pharmaceutics, 2021 Buccal drug delivery is a suitable alternative to invasive routes of drug administration. The buccal administration of insulin for the management of diabetes has received substantial attention worldwide.
Santosh Bashyal +5 more
doaj +1 more source
Ondansetron buccal administration for paediatric use: A comparison between films and wafers [PDF]
International Journal of Pharmaceutics, 2020 The objective of this study was the development of different solid formulations, such as wafers and films, for buccal administration of ondansetron, a selective and potent antagonist of 5-hydroxytryptamine 3 receptors used in children for the treatment of nausea and vomiting.
Barbara Giordani +7 more
openalex +4 more sources
Neither vaginal nor buccal administration of 800 μg misoprostol alters mucosal and systemic immune activation or the cervicovaginal microbiome: a pilot study. [PDF]
Eur J Contracept Reprod Health Care, 2016 Kalams SA +12 more
europepmc +3 more sources
Pharmacokinetics of vaginal versus buccal misoprostol for labor induction at term
Clinical and Translational Science, 2022 The IMPROVE study (NCT02408315) compared the efficacy and safety of vaginal and buccal administration of misoprostol for full‐term, uncomplicated labor induction. This report compares the pharmacokinetics of misoprostol between vaginal and buccal routes.
Yana Vorontsova +10 more
doaj +1 more source
Serum morphine concentrations after buccal and intramuscular morphine administration. [PDF]
British Journal of Clinical Pharmacology, 1987 1. This study compared serum concentrations of morphine after administration of a buccal tablet (25mg) with those after intramuscular injection (10mg). 2. Buccal morphine was administered to eleven healthy volunteers and intramuscular morphine was given to five preoperative surgical patients.
A. P. Fisher, C. FUNG, Michael G. Hanna
openalex +5 more sources
Nano Biomedicine and Engineering, 2021 The present study was conducted to evaluate the impact of calcium oxide-nanoparticles (CaO-NPs) administration at different concentrations on the epithelial thickness, papilla length and number of blood vessels of male Wister rats' buccal mucosa, and the
Bushra Habeeb Al-Maula +5 more
doaj +1 more source
Pharmaceutics, 2021 The buccal mucosa provides an alternative route of drug delivery that can be more beneficial compared to other administration routes. Although numerous studies and reviews have been published on buccal drug delivery, an extensive review of the ...
Apipa Wanasathop +3 more
doaj +1 more source
An Updated Overview of the Emerging Role of Patch and Film-Based Buccal Delivery Systems
Pharmaceutics, 2021 Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery, anatomical and physiological aspects of oral mucosa, and various in ...
Shery Jacob +5 more
doaj +1 more source
Pharmacokinetics of butorphanol in cats after intramuscular and buccal transmucosal administration [PDF]
American Journal of Veterinary Research, 2008 Abstract Objective—To determine the pharmacokinetics of butorphanol in cats following IM and buccal transmucosal (BTM) administration, to determine the relative bioavailability of butorphanol following BTM administration, and to extrapolate a plasma concentration associated with antinociception on the basis of existing data from pharmacologic studies ...
Sean M. Wells +2 more
openalex +4 more sources
Absolute Bioavailability of Microdosed Midazolam After Buccal Administration Is Dependent on Buccal Exposure Time [PDF]
The Journal of Clinical Pharmacology, 2020 AbstractMidazolam is an established probe drug to assess cytochrome P450 3A activity (phenotyping). Microdosed midazolam is increasingly used for this purpose; a buccal formulation might be of advantage, but buccal absorption might occur. We therefore tested in a single‐center, open‐label clinical trial with 12 healthy volunteers the absolute ...
Jana Grass +5 more
openaire +3 more sources