Results 311 to 320 of about 2,104,096 (377)

Pharmacokinetics of Ciclopirox Olamine after Buccal Administration in Rabbits.

Current Drug Delivery, 2017
BACKGROUND Prevalence of oral mucosal fungal infections increases with the frequent administration of antibiotics, corticosteroids and immunosuppressive drugs.
I. Lukášová, J. Muselík, D. Vetchý, J. Gajdziok, M. Gajdošová, J. Juřica, Z. Knotek, K. Hauptman, V. Jekl   +8 more
semanticscholar   +4 more sources

A REVIEW ON BUCCAL MUCOSAL ROUTE OF DRUG ADMINISTRATION

INDIAN DRUGS, 2016
Oral route is the most preferred rote of drug administration. In oral route buccal mucosal route is one of the advantageous routes of drug administration.
Monika Bhatt, G. Bhatt, P. Kothiyal, S. Chaudhary   +3 more
semanticscholar   +2 more sources

In vivo absorption study of ritodrine hydrochloride in the buccal administration to rats

Drug Development and Industrial Pharmacy, 2013
Although ritodrine (RD)-hydrochloride (HCl), named RD-HCl, is widely used in the treatment of premature labor by intravenous prolonged infusion or frequent oral dosing of tablets, those administrations often lower patients' quality of life (QOL) or cause undesirable side effects, such as tachycardia; therefore, in this study, the potential usefulness ...
O. Sakata, H. Onishi
semanticscholar   +3 more sources

Sedative and physiologic effects of tiletamine–zolazepam following buccal administration in cats

Journal of feline medicine and surgery, 2020
Objectives The aim of this study was to describe the sedative and some physiological effects of tiletamine–zolazepam following buccal administration (BA) in cats.
P. Nejamkin, Verónica Cavilla, M. Clausse, Florencia Landivar, A. Lorenzutti, Sofía Martínez, M. D. Del Sole, M. Martin‐Flores   +7 more
semanticscholar   +1 more source

Buccal administration of dexmedetomidine as a preanesthetic in children

Journal of Anesthesia, 2010
The objective of this study was to evaluate the efficacy and safety of buccal dexmedetomidine as a preanesthetic in children, to compare it with diazepam, and to investigate the optimal dosage for buccal dexmedetomidine administration by measuring its serum concentration.We performed a prospective study with 40 children who were assigned to two groups.
Katsuo Terui, Hideki Miyao, Masanori Tamura, Toru Obata, Akio Odaka, Yoshio Sakurai   +5 more
openaire   +3 more sources

Development of mucoadhesive patches for buccal administration of ibuprofen

Journal of Controlled Release, 2004
A new formulation for topical administration of drugs in the oral cavity has been developed using several film-forming and mucoadhesive polymers. The films have been evaluated in terms of swelling, mucoadhesion and organoleptic characteristics. The best film, containing polyvinylpyrrolidone (PVP) as film-forming polymer and carboxymethylcellulose ...
PERIOLI, Luana, AMBROGI, Valeria, Angelici F., RICCI, Maurizio, GIOVAGNOLI, Stefano, Capuccella M., ROSSI, Carlo   +6 more
openaire   +3 more sources

Efficacy of buccal versus intranasal route of administration of midazolam spray in behavior management of preschool dental patients.

Quintessence International, 2021
OBJECTIVE To assess the efficacy of aerosolized midazolam, introduced through buccal versus intranasal mucosa in managing uncooperative children undergoing dental treatment. METHOD AND MATERIALS A crossover randomized controlled clinical trial included
Yousr N Mowafy, Nadia A. Wahba, Tamer M Gho Neim, G. Mahmoud   +3 more
semanticscholar   +1 more source

Bioavailability of flurbiprofen following buccal administration.

Pharmaceutical research, 1991
The buccal absorption of flurbiprofen was evaluated in nine normal volunteers. Twenty milliliters of 2.5 mg/ml flurbiprofen solution (pH 8.03) was administered as a 1-min mouthwash or a 5-min mouthwash or swallowed. Serum was harvested from blood samples taken at specified times over a 12-hr period.
Steven R. Pollock, Dennis J. Stalker
openaire   +3 more sources

In-Situ Gelling Liquid Crystal Mucoadhesive Vehicle for Curcumin Buccal Administration and Its Potential Application in the Treatment of Oral Candidiasis.

Journal of Biomedical Nanotechnology, 2019
The treatments of oral candidiasis involve azole-based antifungals; however, the fungal resistance of these drug compounds has been detected in worldwide. Therefore, the discovery of new molecules from natural sources, such as curcumin, has been reported
B. Fonseca-Santos, B. V. Bonifácio, Taís Maria Baub, M. Gremião, M. Chorilli   +4 more
semanticscholar   +1 more source

Pharmacokinetic evaluation of novel midazolam gel formulations following buccal administration to healthy dogs.

American Journal of Veterinary Research, 2018
OBJECTIVE To determine the physiochemical properties and pharmacokinetics of 3 midazolam gel formulations following buccal administration to dogs. ANIMALS 5 healthy adult hounds. PROCEDURES In phase 1 of a 2-phase study, 2 gel formulations were developed
Mohammed F. Aldawsari, V. Lau, R. J. Babu, R. Arnold, S. Platt   +4 more
semanticscholar   +1 more source